Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | CYP46A1 | Q9Y6A2 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10652939 | 0.99 | OPRM1 (0.42) | OPRM1MEN1KMT2ACASP1CASP7 | |
| SCHEMBL11087626 | 0.95 | OPRM1 (0.42) | OPRM1MEN1KMT2ACASP1CASP7 | |
| Hydrochloric Acid SCHEMBL10656064 | 0.94 | OPRM1 (0.42) | OPRM1MEN1KMT2ACASP1CASP7 | |
| SCHEMBL10653491 | 0.89 | OPRM1 (0.42) | OPRM1MEN1KMT2ACASP1CASP7 | |
| Hydrochloric Acid SCHEMBL10655291 | 0.88 | OPRM1 (0.41) | OPRM1MEN1KMT2ACASP1CASP7 | |
| SCHEMBL11015645 | 0.88 | OPRM1 (0.41) | OPRM1MEN1KMT2ACASP1CASP7 | |
| SCHEMBL10656089 | 0.88 | CASP1 (0.40) | OPRM1MEN1KMT2ACASP1CASP7 | |
| Hydrochloric Acid SCHEMBL10656009 | 0.86 | OPRM1 (0.40) | OPRM1MEN1KMT2ACASP1CASP7 | |
| SCHEMBL10653473 | 0.86 | OPRM1 (0.36) | OPRM1MEN1KMT2ACASP1CASP7 | |
| SCHEMBL10652472 | 0.85 | KMT2A (0.37) | OPRM1MEN1KMT2ACASP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4546105-A | ANALGESICS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1985-10-08 | — | — | US | claimed |