Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TPH1 | P17752 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10651518 | 0.99 | KMT2A (0.38) | KMT2AMEN1GAAGFERF10 | |
| Hydrochloric Acid SCHEMBL10653899 | 0.88 | MEN1 (0.44) | KMT2AMEN1GAAMAPTHPGD | |
| SCHEMBL10656089 | 0.86 | CASP1 (0.40) | KMT2AMEN1TRPV1CASP1CASP7 | |
| SCHEMBL11015645 | 0.86 | OPRM1 (0.41) | KMT2AMEN1ATMTRPV1CASP1 | |
| SCHEMBL11081322 | 0.86 | SMN1; SMN2 (0.39) | KMT2AMEN1F10CASP1CASP7 | |
| SCHEMBL10653284 | 0.86 | TRPV1 (0.37) | KMT2AMEN1F10ATMTRPV1 | |
| Hydrochloric Acid SCHEMBL10652437 | 0.85 | SMN1; SMN2 (0.38) | KMT2AMEN1F10CASP1CASP7 | |
| SCHEMBL10653491 | 0.85 | OPRM1 (0.42) | KMT2AMEN1TRPV1HPGDCASP1 | |
| Hydrochloric Acid SCHEMBL10656009 | 0.85 | OPRM1 (0.40) | KMT2AMEN1ATMTRPV1CASP1 | |
| Hydrochloric Acid SCHEMBL10653411 | 0.85 | TRPV1 (0.37) | KMT2AMEN1F10ATMTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0141968-B1 | PYRROLYLAMINOPIPERIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1988-05-18 | — | — | EP | claimed |