Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | FABP3 | P05413 | 3/20 | 0.46 |
| ▸ | FABP4 | P15090 | 3/20 | 0.46 |
| ▸ | DHODH | Q02127 | 2/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10656122 | 1.00 | KDM4E (0.54) | KDM4ELMNASMN1; SMN2FABP3FABP4 | |
| SCHEMBL10656158 | 0.84 | KDM4E (0.59) | KDM4ELMNASMN1; SMN2FABP3FABP4 | |
| SCHEMBL10656381 | 0.75 | FABP3 (0.50) | KDM4ELMNASMN1; SMN2FABP3FABP4 | |
| SCHEMBL3350429 | 0.75 | KDM4E (0.70) | KDM4ELMNASMN1; SMN2FABP3FABP4 | |
| SCHEMBL10659362 | 0.75 | FABP4 (0.79) | KDM4ELMNASMN1; SMN2FABP3FABP4 | |
| SCHEMBL10661744 | 0.72 | FABP3 (0.47) | KDM4ELMNASMN1; SMN2FABP3FABP4 | |
| SCHEMBL10658967 | 0.72 | FABP3 (0.47) | KDM4ELMNASMN1; SMN2FABP3FABP4 | |
| SCHEMBL3970472 | 0.72 | RXFP1 (0.47) | KDM4EDHODHCASP3 | |
| SCHEMBL3346066 | 0.71 | KDM4E (0.71) | KDM4ELMNASMN1; SMN2FABP3FABP4 | |
| SCHEMBL14390974 | 0.69 | KDM4E (0.78) | KDM4ELMNASMN1; SMN2FABP3FABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4761419-A | ANTILIPEMIC | WARNER-LAMBERT COMPANY (US) | 1988-08-02 | — | — | US | disclosed |