Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.71 |
| ▸ | FABP4 | P15090 | 6/20 | 0.61 |
| ▸ | FABP3 | P05413 | 4/20 | 0.61 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | FABP5 | Q01469 | 5/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | PRNP | P04156 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27726496 | 0.81 | KDM4E (0.54) | KDM4EFABP4FABP3PLA2G2ASMN1; SMN2 | |
| SCHEMBL3350429 | 0.81 | KDM4E (0.70) | KDM4EFABP4FABP3PLA2G2ASMN1; SMN2 | |
| SCHEMBL10656158 | 0.78 | KDM4E (0.59) | KDM4EFABP4FABP3PLA2G2ASMN1; SMN2 | |
| SCHEMBL31058618 | 0.78 | FABP4 (0.59) | KDM4EFABP4FABP3PLA2G2ASMN1; SMN2 | |
| SCHEMBL21083000 | 0.76 | FABP4 (1.00) | KDM4EFABP4FABP3PLA2G2ASMN1; SMN2 | |
| SCHEMBL3322903 | 0.75 | FABP4 (0.73) | KDM4EFABP4FABP3PLA2G2ASMN1; SMN2 | |
| SCHEMBL3321035 | 0.75 | FABP4 (0.62) | KDM4EFABP4FABP3PLA2G2ASMN1; SMN2 | |
| SCHEMBL2820951 | 0.75 | FABP4 (0.82) | KDM4EFABP4FABP3PLA2G2ASMN1; SMN2 | |
| SCHEMBL31058619 | 0.74 | FABP4 (0.60) | KDM4EFABP4FABP3PLA2G2AFABP5 | |
| SCHEMBL3961796 | 0.73 | RXFP1 (0.48) | KDM4ELMNAALDH1A1HTTDHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010056865-A1 | QUINOLINE DERIVATIVES AS ION CHANNEL MODULATORS | GILEAD PALO ALTO, INC. (US) | 2010-05-20 | — | — | WO | claimed |
| WO-2010056865-A1 | QUINOLINE DERIVATIVES AS ION CHANNEL MODULATORS | GILEAD PALO ALTO, INC. (US) | 2010-05-20 | — | — | WO | disclosed |