Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | FABP3 | P05413 | 2/20 | 0.50 |
| ▸ | FABP4 | P15090 | 2/20 | 0.50 |
| ▸ | DHODH | Q02127 | 2/20 | 0.47 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.45 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.44 |
| ▸ | GCGR | P47871 | 4/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10656111 | 0.84 | KDM4E (0.54) | KDM4ELMNASMN1; SMN2FABP3FABP4 | |
| SCHEMBL10656122 | 0.84 | KDM4E (0.54) | KDM4ELMNASMN1; SMN2FABP3FABP4 | |
| SCHEMBL10659362 | 0.80 | FABP4 (0.79) | KDM4ELMNASMN1; SMN2FABP3FABP4 | |
| SCHEMBL3346066 | 0.78 | KDM4E (0.71) | KDM4ELMNASMN1; SMN2FABP3FABP4 | |
| SCHEMBL3961778 | 0.78 | IDO1 (0.44) | KDM4ELMNADHODHPRKAA2GCGR | |
| SCHEMBL8949698 | 0.77 | GCGR (0.56) | PRKAA2GCGR | |
| SCHEMBL10656381 | 0.77 | FABP3 (0.50) | KDM4ELMNASMN1; SMN2FABP3FABP4 | |
| SCHEMBL3961796 | 0.75 | RXFP1 (0.48) | KDM4ELMNADHODHPRKAA2CASP3 | |
| SCHEMBL10661744 | 0.74 | FABP3 (0.47) | KDM4ELMNASMN1; SMN2FABP3FABP4 | |
| SCHEMBL10658967 | 0.74 | FABP3 (0.47) | KDM4ELMNASMN1; SMN2FABP3FABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4761419-A | ANTILIPEMIC | WARNER-LAMBERT COMPANY (US) | 1988-08-02 | — | — | US | disclosed |