Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11049334 | 0.89 | KMT2A (0.49) | HPGDLMNAMAPTKDM4EKMT2A | |
| SCHEMBL6269975 | 0.81 | LMNA (0.75) | HPGDLMNAMAPTCYP3A4KDM4E | |
| SCHEMBL10661318 | 0.80 | SMN1; SMN2 (0.40) | HPGDLMNAMAPTCYP3A4KDM4E | |
| SCHEMBL10661325 | 0.80 | SMN1; SMN2 (0.40) | HPGDLMNAMAPTCYP3A4KDM4E | |
| SCHEMBL11049604 | 0.76 | MAPT (0.49) | HPGDLMNAMAPTCYP3A4KDM4E | |
| SCHEMBL29238855 | 0.76 | NPC1 (0.55) | HPGDLMNAMAPTCYP3A4KDM4E | |
| SCHEMBL2586221 | 0.75 | LMNA (0.70) | HPGDLMNAMAPTCYP3A4KDM4E | |
| SCHEMBL7367690 | 0.74 | SLC22A6 (0.66) | HPGDLMNAMAPTCYP3A4KDM4E | |
| SCHEMBL5990108 | 0.74 | NPC1 (0.53) | HPGDLMNAMAPTKDM4EKMT2A | |
| SCHEMBL7340588 | 0.74 | LMNA (0.59) | HPGDLMNAMAPTCYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4728662-A | DIURETICS, URICOSURICS, HYPOTENSIVES | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1988-03-01 | — | — | US | disclosed |
| US-4673746-A | DIURETICS, HYPOTENSIVES | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1987-06-16 | — | — | US | disclosed |
| US-4487934-A | Method of preparing poly-substituted acylbenzenes | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1984-12-11 | — | — | US | disclosed |
| EP-0041682-B1 | A METHOD OF PREPARING POLY-SUBSTITUTED ACYLBENZENES | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1983-09-21 | — | — | EP | disclosed |
| EP-0045478-A1 | A method of preparing poly-substituted acylbenzenes | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1982-02-10 | — | — | EP | disclosed |
| EP-0041682-A1 | A method of preparing poly-substituted acylbenzenes | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1981-12-16 | — | — | EP | disclosed |
| US-4304941-A | Method of preparing poly-substituted acylbenzenes | HOECHST ROUSSEL PHARMACEUTICALS, INC. (US) | 1981-12-08 | — | — | US | disclosed |