Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | WDR5 | P61964 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5319954 | 0.81 | LMNA (0.66) | ALDH1A1HTTSMN1; SMN2HPGDLMNA | |
| SCHEMBL30972130 | 0.80 | ALDH1A1 (0.79) | ALDH1A1HTTSMN1; SMN2HPGDLMNA | |
| SCHEMBL1276592 | 0.80 | ALDH1A1 (0.79) | ALDH1A1HTTSMN1; SMN2HPGDLMNA | |
| SCHEMBL27565932 | 0.79 | LMNA (0.56) | ALDH1A1HTTSMN1; SMN2HPGDLMNA | |
| SCHEMBL7398748 | 0.78 | ENPP2 (0.61) | ALDH1A1HTTSMN1; SMN2HPGDKMT2A | |
| SCHEMBL7171456 | 0.78 | NPC1 (0.49) | SMN1; SMN2GAADRD2DRD4MAPT | |
| SCHEMBL6273430 | 0.77 | DRD2 (0.62) | HTTSMN1; SMN2LMNAKMT2AGAA | |
| SCHEMBL23709944 | 0.72 | SLC6A4 (0.50) | SMN1; SMN2HPGDLMNAKMT2AGAA | |
| SCHEMBL6914412 | 0.71 | ALDH1A1 (1.00) | ALDH1A1HTTSMN1; SMN2HPGDLMNA | |
| SCHEMBL7363063 | 0.71 | ALDH1A1 (0.81) | ALDH1A1HTTSMN1; SMN2HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0278595-A2 | Fungicides | ZENECA LIMITED (GB) | 1988-08-17 | — | — | EP | disclosed |