SCHEMBL4458254

SCHEMBL4458254

Cc1c(C)c(-c2c(Br)c(Br)c(Br)c(Br)c2Br)c(Br)c(Br)c1Br

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12440900 0.86 LMNA (0.35) TSHR
SCHEMBL4458251 0.86 TSHR (0.33) TSHR
SCHEMBL10977615 0.86 LMNA (0.35) TSHR
SCHEMBL17936458 0.83
SCHEMBL655518 0.82 CA1 (0.33)
SCHEMBL5070588 0.78 LMNA (0.32)
Bromide SCHEMBL518116 0.78 LMNA (0.38)
SCHEMBL10656649 0.78 TSHR (0.41) TSHR
SCHEMBL19072787 0.76
SCHEMBL12403124 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7605207-B2 Heat resistance; using with polystyrene fthermoplastic foams BROMINE COMPOUNDS LTD. (IL) 2009-10-20 US disclosed
US-20080281024-A1 Flame Retardant Bromobenzyl Systems BROMINE COMPOUNDS LTD. (IL) 2008-11-13 US disclosed
EP-1951798-A2 FLAME RETARDANT BROMOBENZYL SYSTEMS Bromine Compounds Ltd. (IL) 2008-08-06 EP disclosed
WO-2007057900-A2 FLAME RETARDANT BROMOBENZYL SYSTEMS BROMINE COMPOUNDS LTD. (IL) 2007-05-24 WO disclosed
EP-0171443-A1 Nuclear-brominated mixtures of dimethyldiphenyl ether isomers, their preparation and their use as flame retardants for synthetics Chemische Fabrik Kalk GmbH (DE) 1986-02-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080281024-A1 Flame Retardant Bromobenzyl Systems PBRM1, PFAS, BPTF TSHR 1876/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.