Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.48 |
| ▸ | CTSK | P43235 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | REN | P00797 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10657304 | 1.00 | CTSS (0.48) | CTSSCTSKALDH1A1CA1CA2 | |
| SCHEMBL10754918 | 0.85 | KLK5 (0.49) | CTSSCTSKREN | |
| SCHEMBL10754932 | 0.85 | KLK5 (0.49) | CTSSCTSKREN | |
| SCHEMBL10754923 | 0.85 | KLK5 (0.49) | CTSSCTSKREN | |
| SCHEMBL9677655 | 0.82 | REN (0.54) | CTSSCTSKBACE1RENCTSD | |
| SCHEMBL9677665 | 0.82 | REN (0.54) | CTSSCTSKBACE1RENCTSD | |
| SCHEMBL10656498 | 0.81 | CTSS (0.42) | CTSSCTSKCA1CA2CA7 | |
| SCHEMBL10662386 | 0.81 | CTSS (0.42) | CTSSCTSKCA1CA2CA7 | |
| SCHEMBL7364723 | 0.79 | CA1 (0.57) | CTSSCTSKCA1CA2CA7 | |
| SCHEMBL12018725 | 0.79 | CA1 (0.57) | CTSSCTSKCA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4757050-A | Urea, amide group-containing | E. R. SQUIBB SONS, INC. (US) | 1988-07-12 | — | — | US | disclosed |