Sugi Predict

Sugi Predict / Compounds / SCHEMBL1065760

SCHEMBL1065760

SCHEMBL1065760

CC(=O)OCCOC(OCCOC(C)=O)OCCOC(C)=O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 5/20 0.52
▸ TSHR P16473 1/20 0.52
▸ CHRM5 P08912 2/20 0.46
▸ CHRM1 P11229 2/20 0.46
▸ CHRM3 P20309 2/20 0.46
▸ PGR P06401 1/20 0.46
▸ CHRM2 P08172 1/20 0.46
▸ CHRM4 P08173 1/20 0.46
▸ HTR1A P08908 1/20 0.46
▸ CHRNB2 P17787 1/20 0.46
▸ TBXA2R P21731 1/20 0.46
▸ CHRNB4 P30926 1/20 0.46
▸ CHRNA3 P32297 1/20 0.46
▸ CHRNA7 P36544 1/20 0.46
▸ CHRNA4 P43681 1/20 0.46
▸ SMN1; SMN2 Q16637 1/20 0.46
▸ CHRNA10 Q9GZZ6 1/20 0.46
▸ CHRNA9 Q9UGM1 1/20 0.46
▸ GALR3 O60755 2/20 0.44
▸ GAA P10253 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL464483 0.91 ALDH1A1 (0.56) ALDH1A1TSHRCHRM5CHRM1CHRM3
SCHEMBL1270603 0.90 ALDH1A1 (0.48) ALDH1A1TSHRCHRM5CHRM1CHRM3
SCHEMBL13120306 0.88 ALDH1A1 (0.46) ALDH1A1TSHRCHRM5CHRM1CHRM3
SCHEMBL64593 0.83 ALDH1A1 (0.68) ALDH1A1TSHRCHRM5CHRM1CHRM3
SCHEMBL421799 0.83 ALDH1A1 (0.42) ALDH1A1TSHRCHRM5CHRM1CHRM3
SCHEMBL4148479 0.82 ALDH1A1 (0.50) ALDH1A1TSHRCHRM5CHRM1CHRM3
SCHEMBL330791 0.82 ALDH1A1 (0.50) ALDH1A1TSHRCHRM5CHRM1CHRM3
SCHEMBL5248026 0.82 ALDH1A1 (0.50) ALDH1A1TSHRCHRM5CHRM1CHRM3
SCHEMBL6668046 0.82 ALDH1A1 (0.50) ALDH1A1TSHRCHRM5CHRM1CHRM3
SCHEMBL8529038 0.80 ALDH1A1 (0.48) ALDH1A1TSHRCHRM5CHRM1CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250000890-A1 TREM COMPOSITIONS AND USES THEREOF FLAGSHIP PIONEERING INNOVATIONS VI, LLC 2025-01-02 — — US disclosed
US-12121531-B2 TREM compositions and uses thereof FLAGSHIP PIONEERING INNOVATIONS VI, LLC (US) 2024-10-22 — — US disclosed
US-20230203510-A1 TREM COMPOSITIONS AND METHODS RELATING THERETO FLAGSHIP PIONEERING INNOVATIONS VI LLC (US) 2023-06-29 — — US disclosed
US-20230203509-A1 TREM COMPOSITIONS AND METHODS RELATING THERETO FLAGSHIP PIONEERING INNOVATIONS VI LLC (US) 2023-06-29 — — US disclosed
CN-116018405-A TREM compositions and related methods 旗舰先锋创新VI有限责任公司 2023-04-25 — — CN disclosed
EP-4158032-A2 TREM COMPOSITIONS AND METHODS RELATING THERETO Flagship Pioneering Innovations VI, LLC (US) 2023-04-05 — — EP disclosed
EP-4158031-A1 TREM COMPOSITIONS AND METHODS RELATING THERETO Flagship Pioneering Innovations VI, LLC (US) 2023-04-05 — — EP disclosed
US-20230054178-A1 TREM COMPOSITIONS AND USES THEREOF FLAGSHIP PIONEERING INNOVATIONS VI, LLC 2023-02-23 — — US disclosed
EP-4136230-A2 TREM COMPOSITIONS AND USES THEREOF Flagship Pioneering Innovations VI, LLC (US) 2023-02-22 — — EP disclosed
CN-115516090-A TREM compositions and uses thereof 旗舰先锋创新VI有限责任公司 2022-12-23 — — CN disclosed
EP-1733035-A2 MODIFIED POLYNUCLEOTIDES FOR REDUCING OFF-TARGET EFFECTS IN RNA INTERFERENCE Dharmacon, Inc. (US) 2006-12-20 — — EP disclosed
EP-1718747-A2 STABILIZED RNAS AS TRANSFECTION CONTROLS AND SILENCING REAGENTS Dharmacon, Inc. (US) 2006-11-08 — — EP disclosed
US-20060223777-A1 Highly functional short hairpin RNA DHARMACON, INC. 2006-10-05 — — US disclosed
EP-1608733-A2 MODIFIED POLYNUCLEOTIDES FOR USE IN RNA INTERFERENCE Dharmacon, Inc. (US) 2005-12-28 — — EP disclosed
WO-2005097992-A2 MODIFIED POLYNUCLEOTIDES FOR REDUCING OFF-TARGET EFFECTS IN RNA INTERFERENCE DHARMACON, INC. (US) 2005-10-20 — — WO disclosed
US-20050223427-A1 Modified polynucleotides for reducing off-target effects in RNA interference DHARMACON, INC. (US) 2005-10-06 — — US disclosed
WO-2005078095-A1 SNP DISCRIMINATORY siRNA DHARMACON, INC. (US) 2005-08-25 — — WO disclosed
WO-2005078094-A2 STABILIZED RNAS AS TRANSFECTION CONTROLS AND SILENCING REAGENTS DHARMACON, INC. (US) 2005-08-25 — — WO disclosed
US-20050176045-A1 SNP discriminatory siRNA DHARMACON, INC. (US) 2005-08-11 — — US disclosed
WO-2004090105-A2 MODIFIED POLYNUCLEOTIDES FOR USE IN RNA INTERFERENCE DHARMACON, INC. (US) 2004-10-21 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230054178-A1 TREM COMPOSITIONS AND USES THEREOF TRMT1, TARBP1, TRMT1L ALDH1A1 4489/4885TSHR 1242/4885CHRM5 3754/4885
US-12121531-B2 TREM compositions and uses thereof TRMT1, TARBP1, TRMT1L ALDH1A1 4489/4885TSHR 1242/4885CHRM5 3754/4885
US-20250000890-A1 TREM COMPOSITIONS AND USES THEREOF TRMT1, TARBP1, TRMT1L ALDH1A1 4489/4885TSHR 1242/4885CHRM5 3754/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.