Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 2/20 | 0.32 |
| ▸ | MGLL | Q99685 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15716024 | 0.85 | APP (0.48) | ALDH1A1RAB9ANPC1CYP1A2CYP3A4 | |
| SCHEMBL27816061 | 0.85 | MEN1 (0.40) | ALDH1A1TAAR1CYP3A4MEN1KMT2A | |
| SCHEMBL2764416 | 0.78 | TDP1 (0.38) | ALDH1A1RAB9ANPC1TDP1NOTUM | |
| SCHEMBL3516703 | 0.78 | CYP1A2 (0.39) | RAB9ANPC1CYP1A2HSD17B10NOTUM | |
| SCHEMBL28159708 | 0.78 | ESR1 (0.46) | ALDH1A1RAB9ANPC1CYP3A4HSD17B10 | |
| SCHEMBL3590067 | 0.78 | RAB9A (0.38) | ALDH1A1RAB9ANPC1HSD17B10NOTUM | |
| SCHEMBL9466142 | 0.76 | ALDH1A1 (0.43) | ALDH1A1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL1435891 | 0.76 | CYP2A6 (0.54) | ALDH1A1CYP1A2CYP3A4HSD17B10ALOX15 | |
| SCHEMBL9466146 | 0.75 | HPGD (0.40) | RAB9ANPC1CYP3A4MEN1KMT2A | |
| SCHEMBL27459678 | 0.75 | MMP3 (0.45) | ALDH1A1NOTUMMMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 269 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118201914-A | 4-Oxo-1, 4-dihydroquinoline-3-carboxylic acid derivatives as PAPD5 and/or PAPD7 inhibitors | 雷多纳治疗公司 | 2024-06-14 | — | — | CN | claimed |
| EP-2986601-B1 | FUNGICIDAL CARBOXAMIDES | DU PONT (US) | 2017-06-07 | — | — | EP | claimed |
| EP-2809668-B1 | 4-(BENZOIMIDAZOL-2-YL)-THIAZOLE COMPOUNDS AND RELATED AZA DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2017-04-12 | — | — | EP | claimed |
| US-9266876-B2 | 4-(benzoimidazol-2-yl)-thiazole compounds and related aza derivatives | ACTELION PHARMACEUTICALS LTD. (CH) | 2016-02-23 | — | — | US | claimed |
| US-20140371204-A1 | 4-(Benzoimidazol-2-yl)-thiazole Compounds and Related Aza Derivatives | IDORSIA PHARMACEUTICALS LTD (CH) | 2014-12-18 | — | — | US | claimed |
| EP-2809668-A1 | 4-(BENZOIMIDAZOL-2-YL)-THIAZOLE COMPOUNDS AND RELATED AZA DERIVATIVES | Actelion Pharmaceuticals Ltd. (CH) | 2014-12-10 | — | — | EP | claimed |
| WO-2013114332-A1 | 4-(BENZOIMIDAZOL-2-YL)-THIAZOLE COMPOUNDS AND RELATED AZA DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2013-08-08 | — | — | WO | claimed |
| EP-2324016-B1 | 3-(N-HETEROCYCLYL)-PYRROLIDINYL-PHENYL-OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | FERRER INT (ES) | 2012-04-25 | — | — | EP | claimed |
| JP-2011526590-A | — | — | 2011-10-13 | — | — | JP | claimed |
| US-20110136829-A1 | 3-(N-HETEROCYCLYL)-PYRROLIDINYL-PHENYL-OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | FERRER INTERNACIONAL, S.A. (ES) | 2011-06-09 | — | — | US | claimed |
| CN-1202890-A | Amino acid derivatives, the preparation and use thereof as endothelia antagonists | BASF AG (DE) | 1998-12-23 | — | — | CN | claimed |
| EP-0874829-A1 | AMINO ACID DERIVATIVES, THE PREPARATION AND USE THEREOF AS ENDOTHELIN ANTAGONISTS | BASF AKTIENGESELLSCHAFT (DE) | 1998-11-04 | — | — | EP | claimed |
| WO-1997038982-A1 | NOVEL CARBOXYLIC ACID DERIVATIVES, THEIR PRODUCTION AND USE | BASF AKTIENGESELLSCHAFT (DE) | 1997-10-23 | — | — | WO | claimed |
| WO-1997012878-A1 | AMINO ACID DERIVATIVES, THE PREPARATION AND USE THEREOF AS ENDOTHELIN ANTAGONISTS | BASF AKTIENGESELLSCHAFT (DE) | 1997-04-10 | — | — | WO | claimed |
| EP-0317979-B1 | Stable detergents containing optical brighteners | CIBA GEIGY AG (CH) | 1994-12-07 | — | — | EP | claimed |
| EP-0322564-B1 | Stable detergents containing optical brighteners | CIBA GEIGY AG (CH) | 1994-06-15 | — | — | EP | claimed |
| US-5290755-A | Plant growth regulators; fungicides | BASF AKTIENGESELLSCHAFT (DE) | 1994-03-01 | — | — | US | claimed |
| US-5035825-A | Stable bleaching detergents containing stilbene fluorescent whitening agents | CIBA-GEIGY CORPORATION (US) | 1991-07-30 | — | — | US | claimed |
| EP-0322564-A2 | Stable detergents containing optical brighteners | CIBA-GEIGY AG (CH) | 1989-07-05 | — | — | EP | claimed |
| EP-0317979-A2 | Stable detergents containing optical brighteners | CIBA-GEIGY AG (CH) | 1989-05-31 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110136829-A1 | 3-(N-HETEROCYCLYL)-PYRROLIDINYL-PHENYL-OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | OXA1L, MRPL21, RPL5 | ALDH1A1 1275/4885RAB9A 1970/4885MAPK1 2309/4885 |
| US-20140371204-A1 | 4-(Benzoimidazol-2-yl)-thiazole Compounds and Related Aza Derivatives | CXCR3, CXCR1, CXCR2 | ALDH1A1 1249/4885RAB9A 2801/4885MAPK1 3385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.