Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CCL2 | P13500 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7643735 | 0.80 | SIGMAR1 (0.33) | HTR2ASIGMAR1HTR6 | |
| Hydrochloric Acid SCHEMBL4457339 | 0.77 | BRD4 (0.37) | HTR2ASIGMAR1BRD4CCL2HTR6 | |
| Hydrochloric Acid SCHEMBL6053912 | 0.75 | BRD4 (0.36) | HTR2ASIGMAR1BRD4CCL2HTR6 | |
| Hydrochloric Acid SCHEMBL7644222 | 0.75 | HTR2A (0.35) | HTR2ASIGMAR1HTR6 | |
| Hydrochloric Acid SCHEMBL7642388 | 0.74 | SIGMAR1 (0.32) | HTR2ASIGMAR1BRD4CCL2HTR6 | |
| Hydrochloric Acid SCHEMBL7615269 | 0.74 | BRD4 (0.35) | HTR2ASIGMAR1BRD4CCL2HTR6 | |
| Hydrochloric Acid SCHEMBL1065901 | 0.69 | BRD4 (0.34) | HTR2ASIGMAR1BRD4CCL2HTR6 | |
| Hydrochloric Acid SCHEMBL3627506 | 0.69 | HTR2A (0.37) | HTR2ASIGMAR1BRD4CCL2HTR6 | |
| Hydrochloric Acid SCHEMBL7642374 | 0.68 | SIGMAR1 (0.33) | HTR2ASIGMAR1HTR6 | |
| Hydrochloric Acid SCHEMBL8534598 | 0.68 | GPR3 (0.32) | HTR2ABRD4CCL2HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6472490-B1 | AN ETHYLENE-AROMATIC VINYL COMPOUND COPOLYMER HAVING AN AROMATIC VINYL COMPOUND CONTENT OF FROM 1 TO LESS THAN 55% BY MOLAR FRACTION, WHICH HAS A HAZE OF AT MOST 41.5% WHEN MOLDED; METHINE DYES | DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2002-10-29 | — | — | US | disclosed |
| US-6348556-B1 | COORDINATION CATALYST OF TRANSITION METAL COMPLEX CONTAINING INDENYL GROUP(S) AND COCATALYST; ISOTACTIC; CATALYSIS, ADDITION COPOLYMERIZATION | DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2002-02-19 | — | — | US | disclosed |
| US-6066709-A | Ethylene-aromatic vinyl compound copolymer and method for its production | DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2000-05-23 | — | — | US | disclosed |
| US-5883213-A | STEREOREGULARITY | DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1999-03-16 | — | — | US | disclosed |