Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | FLT1 | P17948 | 1/20 | 0.35 |
| ▸ | FLT4 | P35916 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10372025 | 0.81 | ALDH1A1 (0.47) | MAPTLMNAPKMKMT2AMEN1 | |
| SCHEMBL10371785 | 0.81 | MAPT (0.39) | MAPTNPSR1MAPK1PKMKMT2A | |
| SCHEMBL10369751 | 0.80 | MAPT (0.39) | MAPTNPSR1LMNAMAPK1PKM | |
| SCHEMBL10522944 | 0.80 | GABRB3 (0.41) | PKMKMT2AMEN1CYP3A4ALDH1A1 | |
| SCHEMBL10562897 | 0.78 | GAA (0.50) | MAPTNPSR1LMNAMAPK1PKM | |
| SCHEMBL10388695 | 0.78 | MAPT (0.37) | MAPTNPSR1MAPK1PKMKMT2A | |
| SCHEMBL10372026 | 0.77 | PKM (0.40) | MAPTNPSR1LMNAMAPK1PKM | |
| SCHEMBL10627213 | 0.76 | GABRB3 (0.40) | MAPTPKMKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL10625006 | 0.76 | L3MBTL1 (0.42) | MAPTLMNAPKMKMT2AMEN1 | |
| SCHEMBL10627175 | 0.75 | TDP1 (0.39) | MAPTNPSR1LMNAPKMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4734125-A | 5-acylamido-1-aryl-pyrazoles, composition containing them and herbicidal method of using them | BAYER AKTIENGESELLSCHAFT (DE) | 1988-03-29 | — | — | US | disclosed |
| EP-0232538-A2 | 5-Acylamido-1-aryl pyrazoles | BAYER AG (DE) | 1987-08-19 | — | — | EP | disclosed |