Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLOD2 | O00469 | 1/20 | 0.51 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | TBXAS1 | P24557 | 13/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL698881 | 0.85 | AGTR1 (0.60) | BDKRB1KDM4EAGTR1RAB9AALDH1A1 | |
| SCHEMBL8241253 | 0.77 | BDKRB1 (0.54) | PLOD2BDKRB1KDM4EALDH1A1TP53 | |
| SCHEMBL9716675 | 0.77 | LIG1 (0.53) | KDM4EAGTR1RAB9AALDH1A1GAA | |
| SCHEMBL10251859 | 0.76 | BDKRB1 (0.75) | BDKRB1KDM4EALDH1A1GAA | |
| SCHEMBL7289960 | 0.76 | AKR1C3 (0.66) | PLOD2ALDH1A1APPGAAHCAR3 | |
| SCHEMBL10660692 | 0.75 | AGTR1 (0.59) | BDKRB1KDM4EAGTR1RAB9AALDH1A1 | |
| SCHEMBL6174044 | 0.75 | AGTR1 (0.59) | BDKRB1KDM4EAGTR1RAB9AALDH1A1 | |
| SCHEMBL8923851 | 0.75 | AKR1C3 (0.57) | KDM4EAGTR1RAB9ATHRBALDH1A1 | |
| SCHEMBL9716698 | 0.75 | AGTR1 (0.49) | KDM4EAGTR1RAB9AALDH1A1GAA | |
| SCHEMBL16474313 | 0.75 | KMT2A (0.71) | BDKRB1KDM4EALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |