Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIG1 | P18858 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL698881 | 0.90 | AGTR1 (0.60) | ALDH1A1AGTR1RAB9AKDM4EKMT2A | |
| SCHEMBL9716698 | 0.86 | AGTR1 (0.49) | ALDH1A1AGTR1RAB9AKDM4EKMT2A | |
| SCHEMBL6174044 | 0.86 | AGTR1 (0.59) | ALDH1A1AGTR1RAB9AKDM4EKMT2A | |
| SCHEMBL8923851 | 0.86 | AKR1C3 (0.57) | ALDH1A1AGTR1RAB9AKDM4EKMT2A | |
| SCHEMBL10660692 | 0.86 | AGTR1 (0.59) | ALDH1A1AGTR1RAB9AKDM4EKMT2A | |
| SCHEMBL6570855 | 0.82 | KMT2A (0.64) | ALDH1A1KDM4EKMT2AMEN1MAPT | |
| SCHEMBL10659074 | 0.82 | KMT2A (0.48) | ALDH1A1AGTR1RAB9AKDM4EKMT2A | |
| SCHEMBL10536918 | 0.79 | AGTR1 (0.51) | ALDH1A1AGTR1RAB9AKDM4EKMT2A | |
| SCHEMBL29620333 | 0.78 | KDM4E (0.71) | ALDH1A1AGTR1RAB9AKDM4EKMT2A | |
| SCHEMBL341645 | 0.78 | KDM4E (0.71) | ALDH1A1AGTR1RAB9AKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0178911-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1992-01-22 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0178911-A2 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1986-04-23 | — | — | EP | disclosed |