Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10666392 | 0.90 | HPGD (0.43) | LMNAHPGDSMN1; SMN2ALDH1A1THRB | |
| SCHEMBL10664496 | 0.88 | HPGD (0.43) | LMNAHPGDSMN1; SMN2ALDH1A1THRB | |
| SCHEMBL10664350 | 0.87 | HPGD (0.47) | LMNAHPGDSMN1; SMN2ALDH1A1THRB | |
| SCHEMBL10664174 | 0.87 | THRB (0.44) | LMNAHPGDSMN1; SMN2ALDH1A1THRB | |
| SCHEMBL10666055 | 0.87 | HPGD (0.44) | LMNAHPGDSMN1; SMN2ALDH1A1THRB | |
| SCHEMBL9831039 | 0.86 | ALDH1A1 (0.33) | LMNAALDH1A1TP53MAPTGAA | |
| SCHEMBL9833022 | 0.84 | MAPT (0.33) | LMNAHPGDALDH1A1HSD17B10TP53 | |
| SCHEMBL9831000 | 0.84 | L3MBTL1 (0.41) | LMNASMN1; SMN2ALDH1A1RAB9AMEN1 | |
| SCHEMBL10665699 | 0.81 | LMNA (0.42) | LMNAHPGDSMN1; SMN2THRBHSD17B10 | |
| SCHEMBL10660546 | 0.81 | HPGD (0.40) | LMNAHPGDSMN1; SMN2ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4755212-A | Novel substituted 1,2,4-triazolo[1,5-a]pyrimidine-2-sulfonamides and compositions and method for inhibiting pollen formation in corn | THE DOW CHEMICAL COMPANY (US) | 1988-07-05 | — | — | US | disclosed |
| US-4741764-A | SUPPRESSION OF NITRIFICATION OF AMMONIUM NITROGEN IN THE SOIL | THE DOW CHEMICAL COMPANY (US) | 1988-05-03 | — | — | US | disclosed |
| US-4740233-A | Substituted 1,2,4-triazolo[1,5-a]-pyrimidine-2-sulfonamides and compositions and methods of controlling undesired vegetation and suppressing the nitrification of ammonium nitrogen in soil | THE DOW CHEMICAL COMPANY (US) | 1988-04-26 | — | — | US | disclosed |