Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 6/20 | 0.41 |
| ▸ | NOS2 | P35228 | 6/20 | 0.41 |
| ▸ | NOS3 | P29474 | 4/20 | 0.41 |
| ▸ | HTR7 | P34969 | 2/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYBB | P04839 | 1/20 | 0.39 |
| ▸ | NCF1 | P14598 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10665610 | 0.92 | HTR7 (0.49) | NOS1NOS2NOS3HTR7HTR1B | |
| SCHEMBL10665348 | 0.87 | MCHR1 (0.40) | KDM4EALDH1A1NCF1MCHR1 | |
| SCHEMBL4901032 | 0.80 | HTR7 (0.55) | NOS1NOS2NOS3HTR7HTR1B | |
| SCHEMBL10755563 | 0.80 | NCF1 (0.42) | NCF1MCHR1 | |
| SCHEMBL10758913 | 0.77 | NCF1 (0.45) | ALDH1A1NCF1MCHR1 | |
| SCHEMBL10665493 | 0.75 | MCHR1 (0.39) | NOS1NOS2NOS3CYBBNCF1 | |
| SCHEMBL10665148 | 0.74 | PDK2 (0.39) | NOS1NOS2NOS3HTR7KDM4E | |
| SCHEMBL10661426 | 0.74 | ALDH1A1 (0.39) | KDM4EALDH1A1SMN1; SMN2CYBBNCF1 | |
| SCHEMBL7529925 | 0.73 | HTR7 (0.64) | HTR7HTR1BKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL10667360 | 0.72 | HTR7 (0.40) | NOS1NOS2NOS3HTR7KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4753933-A | ANXIOLYTIS, ANTIEPILEPTICS, MUSCLE RELAXANTS | RHONE-POULENC SANTE (FR) | 1988-06-28 | — | — | US | disclosed |