Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NCF1 | P14598 | 3/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10662018 | 0.87 | NOS1 (0.41) | MCHR1KDM4EALDH1A1NCF1 | |
| SCHEMBL10665610 | 0.82 | HTR7 (0.49) | NCF1 | |
| SCHEMBL6304828 | 0.80 | HTR7 (0.43) | MCHR1KDM4EALDH1A1TDP1PIM1 | |
| SCHEMBL10758913 | 0.79 | NCF1 (0.45) | MCHR1ALDH1A1TDP1NCF1NPC1 | |
| SCHEMBL10755563 | 0.78 | NCF1 (0.42) | MCHR1NCF1 | |
| SCHEMBL4890383 | 0.74 | KDM4E (0.43) | KDM4EALDH1A1TDP1RAB9A | |
| SCHEMBL2234368 | 0.71 | KDM4E (0.53) | KDM4E | |
| SCHEMBL10665148 | 0.71 | PDK2 (0.39) | MCHR1KDM4EALDH1A1NCF1 | |
| SCHEMBL10665719 | 0.70 | NOS3 (0.53) | MEN1MAPTKMT2A | |
| SCHEMBL7387239 | 0.70 | MCHR1 (0.43) | MCHR1KDM4EALDH1A1TDP1NCF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4753933-A | ANXIOLYTIS, ANTIEPILEPTICS, MUSCLE RELAXANTS | RHONE-POULENC SANTE (FR) | 1988-06-28 | — | — | US | disclosed |