Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 1/20 | 0.36 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 3/20 | 0.32 |
| ▸ | PDE4A | P27815 | 2/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10662924 | 0.83 | ATAD2 (0.40) | ATAD2PGRMAPK14PDE4APDE4B | |
| SCHEMBL9834909 | 0.80 | ATAD2 (0.42) | ATAD2PGRKMT2AMEN1PDE4A | |
| SCHEMBL9835634 | 0.80 | ATAD2 (0.44) | ATAD2PGRPDE4APDE4BPDE4C | |
| SCHEMBL9835231 | 0.78 | ATAD2 (0.40) | ATAD2PGRPDE4APDE4BPDE4C | |
| SCHEMBL9835356 | 0.77 | ATAD2 (0.46) | ATAD2PGRPDE4APDE4BPDE4C | |
| SCHEMBL9834518 | 0.76 | ALDH1A1 (0.36) | CYP1A2CYP2C19LMNACYP2C9POLB | |
| SCHEMBL10668135 | 0.73 | ATAD2 (0.43) | ATAD2PGRPDE4APDE4BPDE4C | |
| SCHEMBL9835182 | 0.71 | ATAD2 (0.49) | ATAD2PGRMAPK14PDE4APDE4B | |
| SCHEMBL9833546 | 0.70 | ATAD2 (0.38) | ATAD2PGRMAPK14KMT2APDE4A | |
| SCHEMBL9835339 | 0.69 | ATAD2 (0.42) | ATAD2PGRMAPK14PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4730003-A | Tricyclic compounds for treating heart and circulatory diseases | BOEHRINGER MANNHEIM GMBH (DE) | 1988-03-08 | — | — | US | disclosed |
| EP-0214592-A2 | Pyrrolobenzimidazoles, process for their preparation and medicaments containing these products | Roche Diagnostics GmbH (DE) | 1987-03-18 | — | — | EP | disclosed |