Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CCR9 | P51686 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10665347 | 0.92 | SMN1; SMN2 (0.40) | MAPK1THRBLMNAHPGDHSD17B10 | |
| SCHEMBL10663834 | 0.91 | THRB (0.43) | MAPK1THRBLMNAALDH1A1HPGD | |
| SCHEMBL10659813 | 0.90 | MAPT (0.41) | MAPK1THRBLMNAALDH1A1HPGD | |
| SCHEMBL10665699 | 0.88 | LMNA (0.42) | MAPK1THRBLMNAHPGDKDM4E | |
| SCHEMBL9831807 | 0.87 | MAPK1 (0.38) | MAPK1THRBLMNAALDH1A1HPGD | |
| SCHEMBL10659543 | 0.86 | HPGD (0.43) | THRBLMNAALDH1A1HPGDKDM4E | |
| SCHEMBL9832194 | 0.85 | MAPK1 (0.41) | MAPK1THRBLMNAALDH1A1KDM4E | |
| SCHEMBL9832897 | 0.85 | ALDH1A1 (0.49) | MAPK1THRBLMNAALDH1A1KDM4E | |
| SCHEMBL10667734 | 0.84 | THRB (0.41) | THRBLMNAALDH1A1HPGDKDM4E | |
| SCHEMBL10661578 | 0.84 | TSHR (0.44) | THRBLMNAALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4755212-A | Novel substituted 1,2,4-triazolo[1,5-a]pyrimidine-2-sulfonamides and compositions and method for inhibiting pollen formation in corn | THE DOW CHEMICAL COMPANY (US) | 1988-07-05 | — | — | US | disclosed |
| US-4741764-A | SUPPRESSION OF NITRIFICATION OF AMMONIUM NITROGEN IN THE SOIL | THE DOW CHEMICAL COMPANY (US) | 1988-05-03 | — | — | US | disclosed |
| US-4740233-A | Substituted 1,2,4-triazolo[1,5-a]-pyrimidine-2-sulfonamides and compositions and methods of controlling undesired vegetation and suppressing the nitrification of ammonium nitrogen in soil | THE DOW CHEMICAL COMPANY (US) | 1988-04-26 | — | — | US | disclosed |