SCHEMBL10667308

SCHEMBL10667308

CC(C)OC(=O)CON=C(c1ccc(F)cc1)C(F)(F)F

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.42
NPSR1 Q6W5P4 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
CYP1A2 P05177 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
LMNA P02545 3/20 0.37
PLOD2 O00469 1/20 0.37
PTBP1 P26599 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
ADRB2 P07550 2/20 0.35
ADRB1 P08588 2/20 0.35
ADRB3 P13945 2/20 0.35
KMT2A Q03164 2/20 0.34
TSHR P16473 1/20 0.34
ALDH1A1 P00352 4/20 0.34
MEN1 O00255 1/20 0.34
RECQL P46063 1/20 0.34
KDM4E B2RXH2 2/20 0.33
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10668548 0.88 SMN1; SMN2 (0.40) MAPTNPSR1L3MBTL1CYP1A2CYP2C9
SCHEMBL10667603 0.85 PLOD2 (0.43) MAPTL3MBTL1LMNAPLOD2PTBP1
SCHEMBL10669808 0.79 NPSR1 (0.48) NPSR1CYP1A2CYP2C9CYP2C19LMNA
SCHEMBL11038316 0.79 PLOD2 (0.41) CYP1A2LMNAPLOD2PTBP1SMN1; SMN2
SCHEMBL9799575 0.79 PLOD2 (0.41) CYP1A2LMNAPLOD2PTBP1SMN1; SMN2
SCHEMBL10668466 0.78 MAPT (0.35) MAPTNPSR1L3MBTL1CYP1A2CYP2C9
SCHEMBL10673355 0.73 L3MBTL1 (0.40) MAPTL3MBTL1SMN1; SMN2KMT2ATSHR
SCHEMBL10842407 0.72 SMN1; SMN2 (0.41) CYP1A2LMNAPLOD2PTBP1SMN1; SMN2
SCHEMBL9864779 0.71 LMNA (0.41) LMNAPLOD2PTBP1SMN1; SMN2KMT2A
SCHEMBL10840904 0.70 LMNA (0.39) MAPTLMNAPLOD2PTBP1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4759789-A Treating locus of plant before or during application of herbicide with oxime ether compound CIBA-GEIGY CORPORATION (US) 1988-07-26 US claimed