SCHEMBL9864779

SCHEMBL9864779

Fc1ccc(CON=C(c2ccc(F)cc2)C(F)(F)F)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.41
PTBP1 P26599 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
S1PR1 P21453 3/20 0.41
NR4A2 P43354 1/20 0.41
IDO1 P14902 2/20 0.40
AGXT P21549 2/20 0.40
MAOB P27338 3/20 0.40
PARP10 Q53GL7 1/20 0.40
POLB P06746 1/20 0.38
PLOD2 O00469 1/20 0.38
CA12 O43570 1/20 0.37
PPARG P37231 1/20 0.36
PPARA Q07869 1/20 0.36
NPC1 O15118 1/20 0.35
CASP3 P42574 1/20 0.35
RAB9A P51151 1/20 0.35
SENP8 Q96LD8 1/20 0.35
SENP7 Q9BQF6 1/20 0.35
SENP6 Q9GZR1 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9799674 0.78 ALDH1A1 (0.39) LMNAPTBP1SMN1; SMN2PLOD2ALDH1A1
SCHEMBL11038316 0.76 PLOD2 (0.41) LMNAPTBP1SMN1; SMN2MAOBPARP10
SCHEMBL9799575 0.76 PLOD2 (0.41) LMNAPTBP1SMN1; SMN2MAOBPARP10
SCHEMBL10842407 0.75 SMN1; SMN2 (0.41) LMNAPTBP1SMN1; SMN2PLOD2ALDH1A1
SCHEMBL10739600 0.74 LMNA (0.36) LMNAPTBP1SMN1; SMN2PLOD2
SCHEMBL10667603 0.74 PLOD2 (0.43) LMNAPTBP1SMN1; SMN2PLOD2NPC1
SCHEMBL10976887 0.74 LMNA (0.36) LMNAPTBP1SMN1; SMN2PLOD2
SCHEMBL10840904 0.73 LMNA (0.39) LMNAPTBP1SMN1; SMN2PLOD2PPARG
SCHEMBL10864019 0.73 IDO1 (0.52) S1PR1IDO1AGXTMAOBPARP10
SCHEMBL16202052 0.73 SMN1; SMN2 (0.47) LMNAPTBP1SMN1; SMN2S1PR1IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5041663-A Plant safening agents CIBA-GEIGY CORPORATION (US) 1991-08-20 US claimed
US-5062879-A 8-AZOLYLMETHYLQUINOLINES AND HERBICIDAL USE THEREOF BASF AKTIENGESELLSCHAFT (DE) 1991-11-05 US disclosed