Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.43 |
| ▸ | ATM | Q13315 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 7/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31553483 | 0.89 | TDP1 (0.48) | TDP1ATMKMT2ANPSR1POLB | |
| SCHEMBL11075153 | 0.86 | ACE (0.38) | TDP1ATMKMT2ANPSR1POLB | |
| SCHEMBL10668564 | 0.84 | KMT2A (0.59) | TDP1ATMKMT2AMEN1PAX8 | |
| SCHEMBL30665183 | 0.83 | TDP1 (0.48) | TDP1ATMKMT2ANPSR1POLB | |
| SCHEMBL12994466 | 0.82 | TDP1 (0.45) | TDP1ATMKMT2ANPSR1POLB | |
| SCHEMBL19982985 | 0.81 | MEN1 (0.52) | TDP1KMT2AMEN1ACEALDH1A1 | |
| SCHEMBL10670788 | 0.81 | MEN1 (0.52) | TDP1KMT2AMEN1ACEALDH1A1 | |
| SCHEMBL19665743 | 0.81 | MEN1 (0.52) | TDP1KMT2AMEN1ACEALDH1A1 | |
| SCHEMBL31553482 | 0.81 | TDP1 (0.50) | TDP1ATMKMT2ANPSR1POLB | |
| SCHEMBL10668227 | 0.80 | CTSK (0.49) | ATMKMT2AMEN1MAPTACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4745124-A | THIO/ESTER PEPTIDES | UNIVERSITY OF MIAMI (US) | 1988-05-17 | — | — | US | disclosed |