Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | ATM | Q13315 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.48 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.48 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.48 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.48 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.47 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16908988 | 0.88 | ACE (0.59) | KMT2AATMITGB3ITGA2BTDP1 | |
| SCHEMBL13702233 | 0.88 | ACE (0.59) | KMT2AATMITGB3ITGA2BTDP1 | |
| SCHEMBL10668227 | 0.87 | CTSK (0.49) | KMT2AATMMEN1MAPK1ITGB3 | |
| SCHEMBL10670788 | 0.84 | MEN1 (0.52) | KMT2AMEN1ITGB3ITGA2BTDP1 | |
| SCHEMBL19665743 | 0.84 | MEN1 (0.52) | KMT2AMEN1ITGB3ITGA2BTDP1 | |
| SCHEMBL19982985 | 0.84 | MEN1 (0.52) | KMT2AMEN1ITGB3ITGA2BTDP1 | |
| SCHEMBL22424958 | 0.84 | PAX8 (0.54) | KMT2AATMMEN1MAPK1TDP1 | |
| SCHEMBL10667341 | 0.84 | TDP1 (0.43) | KMT2AATMMEN1ITGB3ITGA2B | |
| SCHEMBL13956678 | 0.83 | PAX8 (0.52) | TDP1PAX8PSMB5MMP1MMP3 | |
| SCHEMBL19933134 | 0.83 | PTGER4 (0.57) | MAPK1ITGB3ITGA2BTDP1PAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4745124-A | THIO/ESTER PEPTIDES | UNIVERSITY OF MIAMI (US) | 1988-05-17 | — | — | US | disclosed |