Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.49 |
| ▸ | CTSS | P25774 | 1/20 | 0.49 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 2/20 | 0.41 |
| ▸ | FNTB | P49356 | 2/20 | 0.41 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10668564 | 0.87 | KMT2A (0.59) | KMT2AATMMEN1ITGB3ITGA2B | |
| SCHEMBL11036872 | 0.86 | CTSK (0.43) | CTSKCTSSUSP30ITGB3ITGA2B | |
| SCHEMBL19982985 | 0.81 | MEN1 (0.52) | KMT2AMEN1ITGB3ITGA2BACE | |
| SCHEMBL10670788 | 0.81 | MEN1 (0.52) | KMT2AMEN1ITGB3ITGA2BACE | |
| SCHEMBL19665743 | 0.81 | MEN1 (0.52) | KMT2AMEN1ITGB3ITGA2BACE | |
| SCHEMBL10667341 | 0.80 | TDP1 (0.43) | KMT2AATMMEN1ITGB3ITGA2B | |
| SCHEMBL16847748 | 0.79 | CTSS (0.54) | CTSKCTSSFOLH1ITGB3MAPT | |
| SCHEMBL10667361 | 0.79 | TSHR (0.48) | CTSKCTSSFOLH1KMT2AMEN1 | |
| SCHEMBL18099938 | 0.77 | CTSK (0.62) | CTSKCTSSFOLH1FNTAFNTB | |
| SCHEMBL844316 | 0.75 | CTSK (0.73) | CTSKCTSSITGB3ITGA2BACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4745124-A | THIO/ESTER PEPTIDES | UNIVERSITY OF MIAMI (US) | 1988-05-17 | — | — | US | disclosed |