Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | G6PD | P11413 | 1/20 | 0.35 |
| ▸ | CCR6 | P51684 | 1/20 | 0.35 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 3/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.33 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9807146 | 0.82 | ALDH1A1 (0.40) | ALDH1A1MAPTKDM4ETHRBHPGD | |
| SCHEMBL10667969 | 0.80 | ALDH1A1 (0.41) | ALDH1A1MAPTKDM4EHPGDNPSR1 | |
| SCHEMBL14438404 | 0.80 | ALDH1A1 (0.43) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL13990194 | 0.75 | ALDH1A1 (0.50) | ALDH1A1MAPTKDM4EHSD17B10TSHR | |
| SCHEMBL30966777 | 0.75 | ALDH1A1 (0.50) | ALDH1A1MAPTKDM4EHSD17B10TSHR | |
| SCHEMBL10670276 | 0.74 | ELANE (0.39) | ALDH1A1MAPTKDM4ETSHRELANE | |
| SCHEMBL2831664 | 0.73 | SHMT2 (0.44) | ALDH1A1MAPTKDM4EHPGDNPSR1 | |
| SCHEMBL61554 | 0.73 | MAPT (0.42) | ALDH1A1MAPTKDM4ETHRBHPGD | |
| SCHEMBL61415 | 0.73 | ALDH1A1 (0.44) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL22343599 | 0.71 | ELANE (0.47) | ALDH1A1MAPTKDM4EHPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4751327-A | Photoconductive imaging members with unsymmetrical squaraine compounds | XEROX CORPORATION (US) | 1988-06-14 | — | — | US | disclosed |
| US-4624904-A | Photoconductive imaging members with unsymmetrical squaraine compounds containing an hydroxyl group | XEROX CORPORATION (US) | 1986-11-25 | — | — | US | disclosed |