Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | PKM | P14618 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.58 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.57 |
| ▸ | ITGAV | P06756 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | AURKA | O14965 | 4/20 | 0.51 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.51 |
| ▸ | INCENP | Q9NQS7 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14885934 | 0.82 | ALDH1A1 (0.59) | ALDH1A1MEN1KMT2ATDP1POLB | |
| SCHEMBL12177159 | 0.78 | ALDH1A1 (0.67) | ALDH1A1MEN1KMT2ATDP1POLB | |
| SCHEMBL14426564 | 0.78 | PSMB8 (0.92) | ALDH1A1MEN1KMT2ATDP1POLB | |
| SCHEMBL2586820 | 0.78 | PSMB8 (0.92) | ALDH1A1MEN1KMT2ATDP1POLB | |
| SCHEMBL2586823 | 0.78 | PSMB8 (0.92) | ALDH1A1MEN1KMT2ATDP1POLB | |
| SCHEMBL12177305 | 0.78 | MGAM (0.66) | ALDH1A1MEN1KMT2ATDP1POLB | |
| SCHEMBL12717766 | 0.76 | PTPN1 (0.60) | ALDH1A1MEN1KMT2ATDP1POLB | |
| SCHEMBL12177542 | 0.76 | ALDH1A1 (0.64) | ALDH1A1MEN1KMT2ATDP1POLB | |
| SCHEMBL12177123 | 0.76 | ALDH1A1 (0.64) | ALDH1A1MEN1KMT2ATDP1POLB | |
| SCHEMBL12177437 | 0.75 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2ATDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140249191-A1 | Compositions for Controlling Vascularization in Ophthalmological and Dermatological Diseases | AVIENNE PHARMACEUTICALS GMBH (AT) | 2014-09-04 | — | — | US | disclosed |
| US-20140249191-A1 | Compositions for Controlling Vascularization in Ophthalmological and Dermatological Diseases | AVIENNE PHARMACEUTICALS GMBH (AT) | 2014-09-04 | — | — | US | disclosed |
| US-20130102645-A1 | Methods and compositions for controlling vascularization in ophthalmological and dermatological diseases | AVIENNE PHARMACEUTICALS GMBH (AT) | 2013-04-25 | — | — | US | disclosed |
| WO-2013057183-A1 | COMPOSITIONS FOR CONTROLLING VASCULARIZATION IN OPHTHALMOLOGICAL AND DERMATOLOGICAL DISEASES | AVIENNE PHARMACEUTICALS GMBH (AT) | 2013-04-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130102645-A1 | Methods and compositions for controlling vascularization in ophthalmological and dermatological diseases | KDR, REN, FLT1 | ALDH1A1 1466/4885MEN1 2094/4885KMT2A 4438/4885 |
| US-20140249191-A1 | Compositions for Controlling Vascularization in Ophthalmological and Dermatological Diseases | FLT1, KDR, FLT4 | ALDH1A1 735/4885MEN1 1801/4885KMT2A 4419/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.