Crotonic Acid

Crotonic Acid

SCHEMBL10669353

C/C=C/C(=O)[O-].CCCC[Sn+](CCCC)CCCC

nearest known ligand 0.35

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Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.35
CES2 O00748 4/20 0.34
CES1 P23141 4/20 0.34
CA2 P00918 3/20 0.34
THRA P10827 1/20 0.33
THRB P10828 1/20 0.33
FABP3 P05413 2/20 0.32
ATM Q13315 1/20 0.32
BBOX1 O75936 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Crotonic Acid SCHEMBL10669368 1.00 CA1 (0.35) CA1CES2CES1CA2THRA
Fumaric Acid SCHEMBL8846375 0.90 CA1 (0.39) CA1CES2CES1FABP3ATM
Fumaric Acid SCHEMBL8327122 0.90 CA1 (0.39) CA1CES2CES1FABP3ATM
Fumaric Acid SCHEMBL2811329 0.90 CA1 (0.39) CA1CES2CES1FABP3ATM
Fumaric Acid SCHEMBL11053404 0.82 CA1 (0.37) CA1CES2CES1FABP3ATM
Fumaric Acid SCHEMBL8401314 0.82 CES2 (0.43) CES2CES1CA2FABP3
Fumaric Acid SCHEMBL11053356 0.82 CA1 (0.37) CA1CES2CES1FABP3ATM
Fumaric Acid SCHEMBL8397710 0.82 CES2 (0.43) CES2CES1CA2FABP3
Fumaric Acid SCHEMBL8914966 0.81 CA1 (0.33) CA1CES2CES1FABP3ATM
Bicarbonate SCHEMBL8729890 0.80 CA1 (0.46) CA1CES2CES1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4748087-A Plastic laminate of furniture foil and method of making THE WIGGINS TEAPE GROUP LIMITED (GB) 1988-05-31 US disclosed
EP-0183764-B1 COATING SUBSTRATES The Wiggins Teape Group Limited (GB) 1987-11-19 EP disclosed
EP-0183764-A1 COATING SUBSTRATES. WIGGINS TEAPE GROUP LTD (GB) 1986-06-11 EP disclosed
WO-1986000084-A1 COATING SUBSTRATES THE WIGGINS TEAPE GROUP LIMITED (GB) 1986-01-03 WO disclosed