Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | PPOX | P50336 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 4/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.42 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10674485 | 0.90 | FFAR1 (0.46) | FFAR1KMT2AMEN1TTRPPOX | |
| SCHEMBL11095176 | 0.84 | FFAR1 (0.65) | FFAR1KMT2AMEN1TTRPPOX | |
| SCHEMBL10673889 | 0.83 | FFAR1 (0.48) | FFAR1KMT2AMEN1TTRPPOX | |
| SCHEMBL10707742 | 0.82 | FFAR1 (0.54) | FFAR1KMT2AMEN1TTRPPOX | |
| SCHEMBL10668979 | 0.82 | FFAR1 (0.48) | FFAR1KMT2AMEN1TTRPPOX | |
| SCHEMBL10538095 | 0.80 | NPSR1 (0.57) | FFAR1KMT2AMEN1TTRPPOX | |
| SCHEMBL9003844 | 0.80 | FFAR1 (0.60) | FFAR1KMT2AMEN1TTRPPOX | |
| SCHEMBL10969104 | 0.80 | FFAR1 (0.60) | FFAR1KMT2AMEN1TTRPPOX | |
| SCHEMBL11222733 | 0.78 | FFAR1 (0.66) | FFAR1KMT2AMEN1TTRPPOX | |
| SCHEMBL9582439 | 0.77 | FFAR1 (0.58) | FFAR1KMT2AMEN1TTRPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4786317-A | 4-phenoxy-pyridines having herbicidal activity | CELAMERCK GMBH & CO. KG (DE) | 1988-11-22 | — | — | US | disclosed |
| US-4655824-A | Certain trifluoromethoxy-phenoxy-pyridines having herbicidal activity | CELAMERCK GMBH & CO. KG (DE) | 1987-04-07 | — | — | US | disclosed |
| EP-0086375-B1 | PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE | CELAMERCK GmbH & Co. KG (DE) | 1986-04-09 | — | — | EP | disclosed |
| EP-0086375-A2 | Pyridine derivatives, their preparation and use | CELAMERCK GmbH & Co. KG (DE) | 1983-08-24 | — | — | EP | disclosed |