Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Linolenic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 known ✓ | P23219 | 2/20 | 0.69 |
| ▸ | PTGS2 known ✓ | P35354 | 1/20 | 0.69 |
| ▸ | FABP3 | P05413 | 9/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.69 |
| ▸ | F7 | P08709 | 3/20 | 0.69 |
| ▸ | F3 | P13726 | 3/20 | 0.69 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.69 |
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.69 |
| ▸ | PPARG | P37231 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | PPARD | Q03181 | 2/20 | 0.69 |
| ▸ | PPARA | Q07869 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.69 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Linolenic Acid SCHEMBL14576897 | 0.98 | FABP3 (0.97) | FABP3ALDH1A1F7F3CYP19A1 | |
| Linolenic Acid SCHEMBL2928199 | 0.96 | FABP3 (0.96) | FABP3ALDH1A1F7F3CYP19A1 | |
| Linolenic Acid SCHEMBL1060540 | 0.96 | FABP3 (0.96) | FABP3ALDH1A1F7F3CYP19A1 | |
| Linolenic Acid SCHEMBL11790085 | 0.96 | FABP3 (0.96) | FABP3ALDH1A1F7F3CYP19A1 | |
| Linolenic Acid SCHEMBL4917820 | 0.96 | FABP3 (0.96) | FABP3ALDH1A1F7F3CYP19A1 | |
| SCHEMBL25403260 | 0.96 | FABP3 (0.96) | FABP3ALDH1A1F7F3CYP19A1 | |
| Linolenic Acid SCHEMBL4921339 | 0.96 | FABP3 (0.96) | FABP3ALDH1A1F7F3CYP19A1 | |
| Linolenic Acid SCHEMBL447439 | 0.96 | FABP3 (0.96) | FABP3ALDH1A1F7F3CYP19A1 | |
| Linolenic Acid SCHEMBL11594359 | 0.96 | FABP3 (0.96) | FABP3ALDH1A1F7F3CYP19A1 | |
| Linolenic Acid SCHEMBL539075 | 0.96 | FABP3 (0.96) | FABP3ALDH1A1F7F3CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 172 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113336962-A | Quick demulsifier for cationic emulsified asphalt and preparation method and application thereof | 西安博望新材料科技有限公司 | 2021-09-03 | — | — | CN | claimed |
| EP-2329032-B1 | Methods using polypeptides having hydrolase activity | BUNGE OILS INC (US) | 2014-04-30 | — | — | EP | claimed |
| US-8357503-B2 | Hydrolases, nucleic acids encoding them and methods for making and using them | BUNGE OILS, INC. (US) | 2013-01-22 | — | — | US | claimed |
| CN-102325891-A | Hydrolases, nucleic acids encoding them and methods of making and using them | BUNGE OILS INC | 2012-01-18 | — | — | CN | claimed |
| EP-2329032-A2 | HYDROLASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM | Bunge Oils, Inc (US) | 2011-06-08 | — | — | EP | claimed |
| US-20100129882-A1 | HYDROLASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM | BUNGE OILS, INC. | 2010-05-27 | — | — | US | claimed |
| WO-2010024924-A2 | HYDROLASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM | BUNGE OILS, INC. (US) | 2010-03-04 | — | — | WO | claimed |
| EP-4497792-A1 | PENCIL FOR WRITING, PAINTING AND/OR COSMETIC PURPOSES, PENCIL WITH A PENCIL AND METHOD FOR PRODUCING A PENCIL OR CHALK | Faber- Castell AG (DE) | 2025-01-29 | — | — | EP | disclosed |
| CN-118339235-A | Marine biodegradation accelerator having hydrocarbon group and marine biodegradable composition | 日清纺控股株式会社 | 2024-07-12 | — | — | CN | disclosed |
| CN-118317993-A | Marine biodegradable polymer compound, marine biodegradation accelerator, and marine biodegradable resin composition | 日清纺控股株式会社 | 2024-07-09 | — | — | CN | disclosed |
| US-12031039-B2 | Tread rubber composition and pneumatic tire | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2024-07-09 | — | — | US | disclosed |
| CN-118302489-A | Marine biodegradation accelerator having two or more monovalent organic anions, and marine biodegradable composition | 日清纺控股株式会社 | 2024-07-05 | — | — | CN | disclosed |
| EP-3907089-B1 | TREAD RUBBER COMPOSITION AND PNEUMATIC TIRE | SUMITOMO RUBBER IND (JP) | 2024-07-03 | — | — | EP | disclosed |
| EP-0421393-A2 | Resin, compositions, shaped articles, and methods for manufacture | Takeda Chemical Industries, Ltd. (JP) | 1991-04-10 | — | — | EP | disclosed |
| EP-0063631-B1 | DETERGENT-DISPERSANT COMPOSITION FOR LUBRICATING OR FUEL OILS | KYOWA CHEMICAL INDUSTRY CO., LTD. (JP) | 1985-09-04 | — | — | EP | disclosed |
| EP-0063631-A1 | Detergent-dispersant composition for lubricating or fuel oils | KYOWA CHEMICAL INDUSTRY CO., LTD. (JP) | 1982-11-03 | — | — | EP | disclosed |
| US-4340493-A | Detergent-dispersant composition for lubricating or fuel oils | KYOWA CHEMICAL INDUSTRY CO. LTD. (JP) | 1982-07-20 | — | — | US | disclosed |
| US-4253886-A | Corrosion resistant ferromagnetic metal powders and method of preparing the same | FUJI PHOTO FILM CO., LTD. (JP) | 1981-03-03 | — | — | US | disclosed |
| US-4197347-A | High density magnetic recording media | FUJI PHOTO FILM CO., LTD. (JP) | 1980-04-08 | — | — | US | disclosed |
| US-4063000-A | Process for production of ferromagnetic powder | FUJI PHOTO FILM CO., LTD. (JA) | 1977-12-13 | — | — | US | disclosed |