Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10675699 | 0.94 | ALDH1A1 (0.66) | ALDH1A1GAAL3MBTL1TSHRPOLB | |
| SCHEMBL10681406 | 0.85 | ALDH1A1 (0.54) | ALDH1A1GAAL3MBTL1TSHRPOLB | |
| SCHEMBL10673912 | 0.85 | ALDH1A1 (0.54) | ALDH1A1GAAL3MBTL1TSHRPOLB | |
| SCHEMBL10679449 | 0.84 | L3MBTL1 (0.51) | ALDH1A1GAAL3MBTL1TSHRMEN1 | |
| SCHEMBL10678043 | 0.83 | ALDH1A1 (0.67) | ALDH1A1GAAL3MBTL1TSHRPOLB | |
| SCHEMBL10681201 | 0.82 | HSD11B1 (0.64) | ALDH1A1GAAL3MBTL1TSHRMEN1 | |
| SCHEMBL10677456 | 0.82 | ALDH1A1 (0.81) | ALDH1A1GAAL3MBTL1TSHRPOLB | |
| SCHEMBL10670090 | 0.82 | LMNA (0.65) | ALDH1A1GAAL3MBTL1MEN1KMT2A | |
| SCHEMBL10681989 | 0.81 | ALDH1A1 (0.53) | ALDH1A1GAAL3MBTL1TSHRPOLB | |
| SCHEMBL10674987 | 0.81 | HSD11B1 (0.59) | ALDH1A1GAAL3MBTL1TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4766120-A | ANTIINFLAMMATORY AGENTS | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1988-08-23 | — | — | US | disclosed |
| US-4663323-A | Tetrazole derivatives, anti-ulcer composition containing the same and method for treating ulcers | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1987-05-05 | — | — | US | disclosed |
| EP-0035046-B1 | NOVEL TETRAZOLE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF, AND ANTI-ULCER COMPOSITION CONTAINING THE SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1985-10-02 | — | — | EP | disclosed |
| US-4540703-A | Tetrazole derivatives, anti-ulcer composition containing the same and method for treating ulcers | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1985-09-10 | — | — | US | disclosed |
| EP-0035046-A1 | Novel tetrazole derivatives, process for the preparation thereof, and anti-ulcer composition containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1981-09-09 | — | — | EP | disclosed |