Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 5/20 | 0.56 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.56 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.56 |
| ▸ | XDH | P47989 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.53 |
| ▸ | GABRP | O00591 | 2/20 | 0.52 |
| ▸ | GABRD | O14764 | 2/20 | 0.52 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.52 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.52 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.52 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.52 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.52 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.52 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.52 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.52 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.52 |
| ▸ | GABRE | P78334 | 2/20 | 0.52 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.52 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.52 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9327677 | 0.90 | CYP2D6 (0.53) | CYP1A2CYP1A1CYP1B1XDHCYP2D6 | |
| SCHEMBL12835503 | 0.90 | CYP1A2 (0.60) | CYP1A2CYP1A1CYP1B1CYP2D6GABRP | |
| Mitoflaxone SCHEMBL106705 | 0.90 | CYP1A2 (0.62) | CYP1A2CYP1A1CYP1B1CYP2D6GABRP | |
| SCHEMBL9328614 | 0.89 | CYP1A2 (0.59) | CYP1A2CYP1A1CYP1B1XDHCYP2D6 | |
| SCHEMBL12835338 | 0.89 | TDP1 (0.57) | CYP1A2CYP1A1CYP1B1CYP2D6TNKS | |
| SCHEMBL9327546 | 0.88 | CYP1A2 (0.58) | CYP1A2CYP1A1CYP1B1XDHCYP2D6 | |
| SCHEMBL12835627 | 0.88 | CYP2D6 (0.58) | CYP1A2CYP1A1CYP1B1CYP2D6TNKS | |
| SCHEMBL12835324 | 0.88 | TNKS (0.59) | CYP1A2CYP1A1CYP1B1CYP2D6TNKS | |
| SCHEMBL12835505 | 0.88 | CYP1A2 (0.56) | CYP1A2CYP1A1CYP1B1CYP2D6TNKS | |
| SCHEMBL12835292 | 0.87 | CYP2D6 (0.51) | CYP1A2CYP1A1CYP1B1XDHCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0454728-B1 | FLUORINATED FLAVONE ACETIC ACID | UPJOHN CO (US) | 1994-03-16 | — | — | EP | claimed |
| US-5238954-A | Antitumor agents | THE UPJOHN COMPANY (US) | 1993-08-24 | — | — | US | claimed |
| EP-0454728-A1 | FLUORINATED FLAVONE ACETIC ACID. | UPJOHN CO (US) | 1991-11-06 | — | — | EP | claimed |
| WO-1990008143-A1 | FLUORINATED FLAVONE ACETIC ACID | THE UPJOHN COMPANY (US) | 1990-07-26 | — | — | WO | claimed |
| WO-2011023287-A1 | USE OF FAA AND ITS DERIVATIVES IN COSMETICS AND DERMATOLOGY | MERCK PATENT GMBH (DE) | 2011-03-03 | — | — | WO | disclosed |
| EP-0454728-B1 | FLUORINATED FLAVONE ACETIC ACID | UPJOHN CO (US) | 1994-03-16 | — | — | EP | disclosed |
| US-5238954-A | Antitumor agents | THE UPJOHN COMPANY (US) | 1993-08-24 | — | — | US | disclosed |
| EP-0454728-A1 | FLUORINATED FLAVONE ACETIC ACID. | UPJOHN CO (US) | 1991-11-06 | — | — | EP | disclosed |
| WO-1990008143-A1 | FLUORINATED FLAVONE ACETIC ACID | THE UPJOHN COMPANY (US) | 1990-07-26 | — | — | WO | disclosed |