Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 7/20 | 0.59 |
| ▸ | CYP1A1 | P04798 | 6/20 | 0.59 |
| ▸ | CYP1B1 | Q16678 | 6/20 | 0.59 |
| ▸ | GABRP | O00591 | 6/20 | 0.55 |
| ▸ | GABRD | O14764 | 6/20 | 0.55 |
| ▸ | GABRA1 | P14867 | 6/20 | 0.55 |
| ▸ | GABRB1 | P18505 | 6/20 | 0.55 |
| ▸ | GABRG2 | P18507 | 6/20 | 0.55 |
| ▸ | GABRB3 | P28472 | 6/20 | 0.55 |
| ▸ | GABRA5 | P31644 | 6/20 | 0.55 |
| ▸ | GABRA3 | P34903 | 6/20 | 0.55 |
| ▸ | GABRA2 | P47869 | 6/20 | 0.55 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.55 |
| ▸ | GABRA4 | P48169 | 6/20 | 0.55 |
| ▸ | GABRE | P78334 | 6/20 | 0.55 |
| ▸ | GABRA6 | Q16445 | 6/20 | 0.55 |
| ▸ | GABRG1 | Q8N1C3 | 6/20 | 0.55 |
| ▸ | GABRG3 | Q99928 | 6/20 | 0.55 |
| ▸ | GABRQ | Q9UN88 | 6/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12835505 | 0.89 | CYP1A2 (0.56) | CYP1A2CYP1A1CYP1B1CYP2D6CYP3A4 | |
| Mitoflaxone SCHEMBL106705 | 0.89 | CYP1A2 (0.62) | CYP1A2CYP1A1CYP1B1GABRPGABRD | |
| SCHEMBL12835503 | 0.86 | CYP1A2 (0.60) | CYP1A2CYP1A1CYP1B1GABRPGABRD | |
| SCHEMBL7083153 | 0.85 | CYP2D6 (0.54) | CYP1A2CYP1A1CYP1B1CYP2D6CYP3A4 | |
| SCHEMBL12835531 | 0.85 | CYP1A2 (0.54) | CYP1A2CYP1A1CYP1B1CYP2D6CYP3A4 | |
| SCHEMBL9328614 | 0.85 | CYP1A2 (0.59) | CYP1A2CYP1A1CYP1B1GABRPGABRD | |
| SCHEMBL9327546 | 0.84 | CYP1A2 (0.58) | CYP1A2CYP1A1CYP1B1CYP2D6CYP3A4 | |
| SCHEMBL12835629 | 0.83 | CYP2D6 (0.53) | CYP1A2CYP1A1CYP1B1CYP2D6CYP3A4 | |
| SCHEMBL12835338 | 0.82 | TDP1 (0.57) | CYP1A2CYP1A1CYP1B1CYP2D6CYP3A4 | |
| SCHEMBL7087329 | 0.81 | CYP1A2 (0.56) | CYP1A2CYP1A1CYP1B1CYP2D6CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011023287-A1 | USE OF FAA AND ITS DERIVATIVES IN COSMETICS AND DERMATOLOGY | MERCK PATENT GMBH (DE) | 2011-03-03 | — | — | WO | disclosed |
| EP-1328262-A2 | A METHOD TO INCORPORATE N-(4-HYDROXYPHENYL) RETINAMIDE IN LIPOSOMES | Board of Regents, The University of Texas System (US) | 2003-07-23 | — | — | EP | disclosed |
| US-20020143062-A1 | Method to incorporate N-(4-hydroxyphenyl) retinamide in liposomes | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2002-10-03 | — | — | US | disclosed |
| WO-2002032413-A2 | A METHOD TO INCORPORATE N-(4-HYDROXYPHENYL) RETINAMIDE IN LIPOSOMES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2002-04-25 | — | — | WO | disclosed |
| US-5116954-A | Antitumor agents | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1992-05-26 | — | — | US | disclosed |