Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.53 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.53 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.51 |
| ▸ | HRH2 | P25021 | 1/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10504734 | 0.87 | PRMT5 (0.55) | PRMT5WDR77PRMT6HRH2ACE2 | |
| SCHEMBL9866734 | 0.85 | PRMT5 (0.64) | PRMT5WDR77PRMT6ACE2KDM4E | |
| SCHEMBL10868232 | 0.81 | FAAH (0.48) | PRMT5WDR77HRH2FAAHHRH3 | |
| SCHEMBL10668685 | 0.80 | FAAH (0.52) | HRH2FAAHHRH3 | |
| SCHEMBL10811863 | 0.80 | PRMT5 (0.62) | PRMT5WDR77PRMT6ACE2KDM4E | |
| SCHEMBL5167259 | 0.80 | HRH2 (0.59) | PRMT6HRH2FAAHHRH3KDM4E | |
| SCHEMBL13293711 | 0.79 | ALDH1A1 (0.61) | FAAHKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL6140348 | 0.79 | PRMT5 (0.60) | PRMT5WDR77ACE2ALDH1A1SMN1; SMN2 | |
| SCHEMBL5288663 | 0.79 | HRH2 (0.61) | PRMT6HRH2HRH3 | |
| SCHEMBL10527698 | 0.79 | HRH2 (0.61) | PRMT6HRH2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4727081-A | ANTIULCER AGENTS | LUDWIG HEUMANN & CO. GMBH (DE) | 1988-02-23 | — | — | US | disclosed |
| EP-0180754-A2 | 3,4-Diazole derivatives, process for their preparation and medicines containing these compounds | LUDWIG HEUMANN & CO GMBH (DE) | 1986-05-14 | — | — | EP | disclosed |