Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.55 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.55 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.50 |
| ▸ | HRH2 | P25021 | 1/20 | 0.50 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10670904 | 0.87 | PRMT5 (0.53) | PRMT5WDR77PRMT6HRH2ACE2 | |
| SCHEMBL28508097 | 0.82 | PRMT5 (0.53) | PRMT5WDR77FAAH | |
| SCHEMBL28508095 | 0.82 | PRMT5 (0.53) | PRMT5WDR77FAAH | |
| SCHEMBL9866734 | 0.82 | PRMT5 (0.64) | PRMT5WDR77PRMT6ACE2SMN1; SMN2 | |
| SCHEMBL13293711 | 0.81 | ALDH1A1 (0.61) | FAAHSMN1; SMN2ALDH1A1KDM4ESIGMAR1 | |
| SCHEMBL6140348 | 0.81 | PRMT5 (0.60) | PRMT5WDR77ACE2SMN1; SMN2ALDH1A1 | |
| SCHEMBL13004090 | 0.80 | ALDH1A1 (0.60) | PRMT6SMN1; SMN2ALDH1A1KDM4ESIGMAR1 | |
| SCHEMBL13272657 | 0.80 | HRH2 (0.55) | HRH2SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL13574574 | 0.80 | PRMT5 (0.65) | PRMT5WDR77ACE2SMN1; SMN2KDM4E | |
| SCHEMBL13574575 | 0.80 | PRMT5 (0.65) | PRMT5WDR77ACE2SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0159012-B1 | SULFONAMIDINES, A PROCESS FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FERRER INTERNACIONAL, S.A. (ES) | 1989-02-01 | — | — | EP | disclosed |
| EP-0159012-A2 | Sulfonamidines, a process for preparing them and pharmaceutical compositions containing them | FERRER INTERNACIONAL, S.A. (ES) | 1985-10-23 | — | — | EP | disclosed |