Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 7/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | GABRE | P78334 | 1/20 | 0.41 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7307095 | 0.89 | GABRA1 (0.41) | OPRK1GABRA1GABRA5GABRA3GABRA2 | |
| SCHEMBL7309855 | 0.88 | LMNA (0.43) | OPRK1KCNH2PDE4DCHRM1LMNA | |
| SCHEMBL7314761 | 0.85 | LMNA (0.45) | OPRK1GABRA1GABRA5GABRA3GABRA2 | |
| SCHEMBL7310869 | 0.84 | TSHR (0.35) | ALDH1A1HPGDHSD17B10 | |
| SCHEMBL10674727 | 0.83 | OPRK1 (0.43) | OPRK1GABRA1GABRA5GABRA3GABRA2 | |
| SCHEMBL7309396 | 0.77 | GABRA1 (0.46) | OPRK1GABRA1GABRA5GABRA3GABRA2 | |
| SCHEMBL7303999 | 0.76 | CHRM1 (0.41) | OPRK1GABRA1GABRA5GABRA3GABRA2 | |
| SCHEMBL7307967 | 0.76 | ADRA1A (0.44) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL20473325 | 0.75 | CHRM1 (0.38) | OPRK1PDE4DNR1I2ADORA3ALDH1A1 | |
| SCHEMBL20473281 | 0.75 | CYP1A2 (0.35) | CHRM1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4739049-A | Phosphorylation of cyclic amides | HOFFMANN-LA ROCHE INC. (US) | 1988-04-19 | — | — | US | disclosed |