Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | DHODH | Q02127 | 2/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MOK | Q9UQ07 | 1/20 | 0.42 |
| ▸ | TACR3 | P29371 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10680747 | 0.82 | TACR3 (0.53) | TSHRDHODHKDM4ELMNAMOK | |
| Methane SCHEMBL10505710 | 0.80 | BACE1 (0.61) | TSHRNPC1RAB9ADHODHBACE1 | |
| SCHEMBL7925057 | 0.79 | TSHR (0.51) | TSHRDHODHKDM4ELMNAMOK | |
| SCHEMBL10678524 | 0.78 | TSHR (0.54) | TSHRDHODHL3MBTL1KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL10672938 | 0.78 | TSHR (0.50) | TSHRDHODHKDM4ELMNAMOK | |
| SCHEMBL10760505 | 0.78 | TSHR (0.62) | TSHRNPC1RAB9ADHODHMEN1 | |
| Hydrochloric Acid SCHEMBL10692591 | 0.75 | DHODH (0.51) | TSHRDHODHKDM4ELMNATACR3 | |
| Hydrochloric Acid SCHEMBL10682720 | 0.73 | TACR3 (0.48) | TSHRDHODHMOKTACR3 | |
| SCHEMBL10608979 | 0.72 | L3MBTL1 (0.57) | TSHRNPC1RAB9AL3MBTL1MEN1 | |
| SCHEMBL20809020 | 0.71 | DHODH (0.57) | TSHRDHODHKDM4ELMNATACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4788204-A | TRANQUILIZERS; ANTICONVULSANTS; ANGINA AND IMMUNODIFICIENCY TREATMENTS | RHONE-POULENC SANTE (FR) | 1988-11-29 | — | — | US | disclosed |
| US-4788199-A | ANXIOLYTICS, ANTICONVULSANTS, ANTIANGINA AGENTS | RHONE-POULENC SANTE (FR) | 1988-11-29 | — | — | US | disclosed |