Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MOK | Q9UQ07 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10675279 | 0.80 | TSHR (0.47) | BACE1L3MBTL1NPC1RAB9ADHODH | |
| SCHEMBL10760505 | 0.79 | TSHR (0.62) | CYP3A4NPC1RAB9ADHODHALDH1A1 | |
| SCHEMBL10608979 | 0.77 | L3MBTL1 (0.57) | L3MBTL1NPC1RAB9AALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL10677070 | 0.76 | KDM4E (0.51) | L3MBTL1NPC1RAB9ADHODHALDH1A1 | |
| SCHEMBL10769477 | 0.75 | MOK (0.52) | L3MBTL1NPC1RAB9ADHODHALDH1A1 | |
| SCHEMBL10671292 | 0.75 | PDE10A (0.58) | CYP3A4DHODHLMNATSHRKDM4E | |
| SCHEMBL10676850 | 0.75 | TSHR (0.48) | L3MBTL1ALDH1A1MAPTLMNATSHR | |
| Hydrochloric Acid SCHEMBL10682090 | 0.74 | MOK (0.51) | L3MBTL1NPC1RAB9ADHODHALDH1A1 | |
| Hydrochloric Acid SCHEMBL26649569 | 0.74 | PDE10A (0.56) | CYP3A4DHODHLMNATSHRKDM4E | |
| SCHEMBL10674388 | 0.73 | CYP2C9 (0.55) | L3MBTL1NPC1RAB9ADHODHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210084-B1 | AMIDES, PROCESSES FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | RHONE-POULENC SANTE (FR) | 1989-02-08 | — | — | EP | disclosed |
| EP-0210084-A1 | Amides, processes for their preparation and medicaments containing them | RHONE-POULENC SANTE (FR) | 1987-01-28 | — | — | EP | disclosed |