SCHEMBL10675403

SCHEMBL10675403

CCOC(=O)C1=C(C)NC(C)=C(C(=O)OC)C1c1cc(OC)cc(OC)c1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.69
ALDH1A1 P00352 3/20 0.69
HSD17B10 Q99714 3/20 0.69
LMNA P02545 2/20 0.69
HPGD P15428 2/20 0.69
GAA P10253 1/20 0.69
ADORA3 P0DMS8 2/20 0.67
CACNA1F O60840 1/20 0.61
CACNA1D Q01668 1/20 0.61
CACNA1S Q13698 1/20 0.61
CACNA1C Q13936 1/20 0.61
HIF1A Q16665 5/20 0.58
CYP1A2 P05177 4/20 0.58
CYP3A4 P08684 4/20 0.58
CYP2C9 P11712 4/20 0.58
CYP2C19 P33261 4/20 0.58
MEN1 O00255 3/20 0.58
KMT2A Q03164 3/20 0.58
TSHR P16473 3/20 0.58
MAPT P10636 2/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11819175 0.96 KDM4E (0.74) KDM4EALDH1A1HSD17B10LMNAHPGD
SCHEMBL7814802 0.82 KDM4E (1.00) KDM4EALDH1A1HSD17B10LMNAHPGD
SCHEMBL20610477 0.81 ADORA3 (1.00) KDM4EALDH1A1HSD17B10LMNAHPGD
SCHEMBL24624821 0.80 ALDH1A1 (0.56) KDM4EALDH1A1HSD17B10LMNAHPGD
SCHEMBL11824598 0.80 ADORA3 (0.73) KDM4EALDH1A1HSD17B10LMNAHPGD
SCHEMBL9501645 0.80 ADORA3 (0.78) KDM4EALDH1A1HSD17B10LMNAHPGD
SCHEMBL7158354 0.80 ADORA3 (0.78) KDM4EALDH1A1HSD17B10LMNAHPGD
SCHEMBL11814442 0.80 KDM4E (0.63) KDM4EALDH1A1HSD17B10LMNAHPGD
SCHEMBL7341782 0.79 CACNA1D (0.67) KDM4EALDH1A1HSD17B10LMNAHPGD
SCHEMBL3330194 0.78 ADORA3 (0.76) KDM4EALDH1A1HSD17B10LMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4722931-A MUSCLE RELAXANTS LABORATORIOS DELAGRANGE (ES) 1988-02-02 US disclosed