Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.36 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.36 |
| ▸ | HTR1B | P28222 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10674278 | 0.88 | ALDH1A1 (0.38) | ALDH1A1MAPK1HTR1BRAB9AKDM4E | |
| SCHEMBL10681592 | 0.86 | HTR1B (0.41) | ALDH1A1SSTR2SSTR4MAPK1HTR1B | |
| SCHEMBL10682647 | 0.84 | HTR1B (0.42) | ALDH1A1MAPK1HTR1BKDM4ELMNA | |
| SCHEMBL11019939 | 0.83 | HTR1B (0.46) | ALDH1A1SSTR2SSTR4MAPK1HTR1B | |
| SCHEMBL10677366 | 0.82 | HTR1B (0.44) | ALDH1A1SSTR2SSTR4MAPK1HTR1B | |
| SCHEMBL10678598 | 0.82 | HTR1B (0.45) | ALDH1A1MAPK1HTR1BRAB9ATP53 | |
| SCHEMBL11021541 | 0.81 | RAB9A (0.47) | ALDH1A1SSTR2SSTR4MAPK1HTR1B | |
| SCHEMBL10679823 | 0.80 | HPGD (0.56) | ALDH1A1MAPK1RAB9ALMNAHPGD | |
| SCHEMBL11018370 | 0.79 | L3MBTL1 (0.42) | ALDH1A1SSTR2SSTR4MAPK1HTR1B | |
| SCHEMBL11019544 | 0.78 | HTR1B (0.47) | ALDH1A1SSTR2SSTR4MAPK1HTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792570-A | 3- and 4-biphenyloxyaminoalkanes and related compounds as anti-inflammatory and analgetic agents | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0157652-A1 | 2-, 3- And 4-biphenyloxyaminoalkanes and related compounds, their preparation and uses, and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1985-10-09 | — | — | EP | disclosed |