Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11319239 | 0.82 | LMNA (0.57) | LMNAGABRA1GABRA5GABRA3GABRA2 | |
| SCHEMBL11399009 | 0.82 | GABRA1 (0.57) | SMN1; SMN2LMNAMAPTALDH1A1MAPK1 | |
| SCHEMBL7306805 | 0.74 | GABRA1 (0.69) | LMNAGABRA1GABRA5GABRA3GABRA2 | |
| SCHEMBL7548596 | 0.72 | DAO (0.40) | SMN1; SMN2LMNAMAPTALDH1A1RAB9A | |
| SCHEMBL7551382 | 0.70 | NSD2 (0.40) | LMNAMAPTALDH1A1MEN1TP53 | |
| SCHEMBL6527541 | 0.70 | GABRA1 (0.55) | SMN1; SMN2LMNAMAPTGABRA1GABRA5 | |
| SCHEMBL32681120 | 0.70 | GABRA1 (0.55) | SMN1; SMN2LMNAMAPTGABRA1GABRA5 | |
| SCHEMBL7548112 | 0.70 | MEN1 (0.33) | MAPTALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL11374130 | 0.67 | CHRM1 (0.41) | LMNAMAPK1HSD17B10HPGD | |
| SCHEMBL2846056 | 0.66 | KMT2A (0.47) | SMN1; SMN2LMNAMAPTALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4739049-A | Phosphorylation of cyclic amides | HOFFMANN-LA ROCHE INC. (US) | 1988-04-19 | — | — | US | disclosed |