Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.57 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.57 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.57 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.57 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.57 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | CCNB2 | O95067 | 4/20 | 0.41 |
| ▸ | CDK1 | P06493 | 4/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 4/20 | 0.41 |
| ▸ | GSK3B | P49841 | 4/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 4/20 | 0.41 |
| ▸ | CCNB3 | Q8WWL7 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | TGM2 | P21980 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11319239 | 0.85 | LMNA (0.57) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL2846056 | 0.84 | KMT2A (0.47) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL10675729 | 0.82 | SMN1; SMN2 (0.39) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL7551382 | 0.72 | NSD2 (0.40) | KMT2AMEN1LMNATGM2CES1 | |
| SCHEMBL7548596 | 0.72 | DAO (0.40) | LMNAMAPTSMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL32681120 | 0.72 | GABRA1 (0.55) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL638723 | 0.72 | GABRA1 (1.00) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL6527541 | 0.72 | GABRA1 (0.55) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL31696096 | 0.72 | GABRA1 (1.00) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL7548112 | 0.70 | MEN1 (0.33) | KMT2AMEN1MAPTALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4246270-A | TRANQUILIZERS, MUSCLE RELAXANTS, AND SEDATIVES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-01-20 | — | — | US | disclosed |
| US-4120856-A | REACTING 3-HYDROXY-BENZODIAZEPINES WITH AMINOSULFUR TRIFLUORIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1978-10-17 | — | — | US | disclosed |