Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.42 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10682007 | 0.88 | ALDH1A1 (0.56) | ALDH1A1MAPTL3MBTL1LMNAGAA | |
| SCHEMBL10683554 | 0.86 | UCHL1 (0.43) | ALDH1A1MAPTL3MBTL1LMNAGAA | |
| SCHEMBL10679912 | 0.85 | CDC7 (0.40) | ALDH1A1MAPTL3MBTL1LMNAGAA | |
| SCHEMBL10680630 | 0.83 | NPC1 (0.34) | ALDH1A1MAPTLMNAGAANPC1 | |
| SCHEMBL10684372 | 0.80 | MAPT (0.34) | ALDH1A1MAPTL3MBTL1LMNAGAA | |
| SCHEMBL10674925 | 0.78 | ALDH1A1 (0.53) | ALDH1A1MAPTL3MBTL1LMNAGAA | |
| SCHEMBL10679716 | 0.77 | ALDH1A1 (0.52) | ALDH1A1MAPTL3MBTL1LMNAGAA | |
| SCHEMBL7380127 | 0.77 | PDE3B (0.46) | ALDH1A1MAPTLMNAGAAPOLB | |
| SCHEMBL5901793 | 0.76 | GAA (0.73) | ALDH1A1MAPTL3MBTL1LMNAGAA | |
| SCHEMBL10684544 | 0.76 | CDK5 (0.54) | ALDH1A1MAPTL3MBTL1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4769380-A | Cardiotonic 5-benzoyl-1,2-dihydro-2-oxo-3-pyridinecarboxylates | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-09-06 | — | — | US | disclosed |