Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL1 | P09936 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10679912 | 0.88 | CDC7 (0.40) | UCHL1GAAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL10681150 | 0.86 | UCHL1 (0.50) | UCHL1GAAKDM4EHPGDHSD17B10 | |
| SCHEMBL10680630 | 0.86 | NPC1 (0.34) | GAAKDM4EHPGDHSD17B10ALDH1A1 | |
| SCHEMBL10676997 | 0.86 | ALDH1A1 (0.53) | GAAKDM4EHPGDALDH1A1NPC1 | |
| SCHEMBL10684372 | 0.83 | MAPT (0.34) | UCHL1GAAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7380127 | 0.80 | PDE3B (0.46) | GAAKDM4EHPGDHSD17B10ALDH1A1 | |
| SCHEMBL10680827 | 0.76 | RAB9A (0.35) | GAAKDM4EHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL10676837 | 0.75 | CDC7 (0.42) | UCHL1GAAHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL10684520 | 0.75 | UCHL1 (0.46) | UCHL1GAAKDM4EHPGDHSD17B10 | |
| SCHEMBL10995339 | 0.74 | KDM4E (0.46) | GAAKDM4EHPGDHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4769380-A | Cardiotonic 5-benzoyl-1,2-dihydro-2-oxo-3-pyridinecarboxylates | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-09-06 | — | — | US | disclosed |