Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA2 | P47869 | 7/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 7/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 7/20 | 0.38 |
| ▸ | GABRP | O00591 | 3/20 | 0.38 |
| ▸ | GABRD | O14764 | 3/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.38 |
| ▸ | GABRE | P78334 | 3/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.38 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.38 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.38 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10800326 | 0.92 | GABRA2 (0.35) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL10684431 | 0.91 | HSD11B1 (0.36) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL9774928 | 0.91 | GABRA2 (0.38) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL10679027 | 0.90 | GABRA2 (0.35) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL9774979 | 0.89 | MEN1 (0.36) | ALDH1A1ATMMEN1TSHRKMT2A | |
| SCHEMBL9774740 | 0.86 | ALDH1A1 (0.33) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL9774851 | 0.86 | MRGPRX4 (0.34) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL9774771 | 0.86 | SCD (0.36) | ALDH1A1ATMMEN1TSHRKMT2A | |
| SCHEMBL9774892 | 0.86 | ALDH1A1 (0.35) | ALDH1A1ATMMEN1TSHRKMT2A | |
| SCHEMBL9730810 | 0.86 | GABRB3 (0.37) | GABRA2GABRB2GABRB3GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0216541-A1 | Aryl pyridones | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-04-01 | — | — | EP | claimed |
| CN-86106734-A | ARYL PYRIDONES | — | 1987-04-01 | — | — | CN | claimed |
| US-4725607-A | MITICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-02-16 | — | — | US | disclosed |
| EP-0216541-A1 | Aryl pyridones | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-04-01 | — | — | EP | disclosed |
| CN-86106734-A | ARYL PYRIDONES | — | 1987-04-01 | — | — | CN | disclosed |