Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.61 |
| ▸ | MGAM | O43451 | 1/20 | 0.61 |
| ▸ | SI | P14410 | 1/20 | 0.61 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1413000 | 0.88 | GAA (0.48) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL15228762 | 0.82 | GAA (0.50) | GAAMGAMSIMGAM2MAPT | |
| SCHEMBL11319534 | 0.82 | ALDH1A1 (0.44) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL9865139 | 0.81 | GAA (0.46) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL28675119 | 0.80 | GAA (0.46) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL7713280 | 0.80 | GAA (0.55) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL24611006 | 0.78 | GAA (0.56) | GAAMGAMSIMGAM2MAPT | |
| Malonic Acid Diethyl Ester SCHEMBL9439825 | 0.78 | GAA (0.88) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL13638352 | 0.77 | GAA (0.42) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL2539602 | 0.77 | GAA (0.42) | GAAMGAMSIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250340541-A1 | METHODS OF PREPARING MODULATORS OF THR-BETA | ALIGOS THERAPEUTICS, INC. (US) | 2025-11-06 | — | — | US | disclosed |
| WO-2025137568-A1 | MODULATORS OF THR-BETA AND METHODS OF USE THEREOF | ALIGOS THERAPEUTICS, INC. (US) | 2025-06-26 | — | — | WO | disclosed |
| US-20250206725-A1 | MODULATORS OF THR-BETA AND METHODS OF USE THEREOF | ALIGOS THERAPEUTICS, INC. (US) | 2025-06-26 | — | — | US | disclosed |
| WO-2021000933-A1 | PYRIMIDINONE COMPOUNDS AS CHYMASE INHIBITORS AND APPLICATION THEREOF | 南京明德新药研发有限公司 | 2021-01-07 | — | — | WO | disclosed |
| US-4772704-A | ANTIULCER AGENTS | BRISTOL-MYERS COMPANY (US) | 1988-09-20 | — | — | US | disclosed |
| US-4448961-A | Substituted anilino pyrimidines | ZOECON CORPORATION (US) | 1984-05-15 | — | — | US | disclosed |
| US-4411839-A | α-Cyano-β-(trisubstituted phenylhydrazino)-n-ethoxycarbonylacrylamides | ZOECON CORPORATION (US) | 1983-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250206725-A1 | MODULATORS OF THR-BETA AND METHODS OF USE THEREOF | THRB, THRA, TTR | GAA 1578/4885MGAM 3633/4885SI 569/4885 |
| US-20250340541-A1 | METHODS OF PREPARING MODULATORS OF THR-BETA | THRB, THRA, THRAP3 | GAA 929/4885MGAM 2200/4885SI 570/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.