SCHEMBL1067942

SCHEMBL1067942

COC1C(=O)c2c(O)cc(O)cc2OC1c1ccc(O)c(O)c1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.69
CYP3A4 P08684 5/20 0.69
ALOX15 P16050 5/20 0.69
HSD17B10 Q99714 4/20 0.69
RECQL P46063 3/20 0.69
POLB P06746 3/20 0.69
MEN1 O00255 3/20 0.69
KMT2A Q03164 3/20 0.69
KDM4E B2RXH2 3/20 0.69
GAA P10253 3/20 0.69
CYP1A2 P05177 2/20 0.69
MAPK1 P28482 2/20 0.69
SOST Q9BQB4 2/20 0.69
ALOX12 P18054 2/20 0.69
HIF1A Q16665 2/20 0.69
NFKB1 P19838 1/20 0.69
P4HB P07237 1/20 0.66
THRB P10828 1/20 0.58
HTT P42858 1/20 0.58
BLM P54132 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30256424 1.00 MAPT (0.69) MAPTCYP3A4ALOX15HSD17B10RECQL
SCHEMBL31527939 1.00 MAPT (0.69) MAPTCYP3A4ALOX15HSD17B10RECQL
SCHEMBL31527994 0.90 MEN1 (0.56) MAPTCYP3A4ALOX15HSD17B10RECQL
SCHEMBL25439511 0.90 CBS (0.68) MAPTCYP3A4ALOX15HSD17B10RECQL
SCHEMBL25439509 0.90 CBS (0.68) MAPTCYP3A4ALOX15HSD17B10RECQL
SCHEMBL30576365 0.90 CBS (0.68) MAPTCYP3A4ALOX15HSD17B10RECQL
3,4'-O-Dimethylquercetin SCHEMBL25437986 0.89 CYP3A4 (0.60) MAPTCYP3A4ALOX15HSD17B10RECQL
SCHEMBL1066027 0.89 XDH (0.56) MAPTCYP3A4ALOX15HSD17B10RECQL
3,4'-O-Dimethylquercetin SCHEMBL25437988 0.89 CYP3A4 (0.60) MAPTCYP3A4ALOX15HSD17B10RECQL
SCHEMBL31162777 0.89 CYP2C9 (0.62) MAPTCYP3A4ALOX15HSD17B10RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120114583-A1 USE OF DIHYDROQUERCETIN AND AT LEAST ONE AMINO ACID TO POSITIVELY INFLUENCE THE NATURAL PIGMENTATION PROCESS HENKEL AG & CO. KGAA (DE) 2012-05-10 US claimed
WO-2023172394-A1 FLAVANONE COMPOUNDS AND THEIR USE AS FLAVOR MODIFIERS FIRMENICH INCORPORATED (US) 2023-09-14 WO disclosed
US-20150191430-A1 CONJUGATES OF HUPERZINE AND ANALOGS THEREOF BISCAYNE NEUROTHERAPEUTICS, INC. 2015-07-09 US disclosed
EP-2456417-A2 USE OF CARNITINE AND DIHYDROQUERCITIN TO POSITIVELY INFLUENCE THE NATURAL PIGMENTATION PROCESS Henkel AG & Co. KGaA (DE) 2012-05-30 EP disclosed
EP-2456418-A2 USE OF DIHYDROQUERCETIN AND AT LEAST ONE AMINO ACID TO POSITIVELY INFLUENCE THE NATURAL PIGMENTATION PROCESS Henkel AG & Co. KGaA (DE) 2012-05-30 EP disclosed
US-20120114583-A1 USE OF DIHYDROQUERCETIN AND AT LEAST ONE AMINO ACID TO POSITIVELY INFLUENCE THE NATURAL PIGMENTATION PROCESS HENKEL AG & CO. KGAA (DE) 2012-05-10 US disclosed
US-20120115944-A1 USE OF CARNITINE AND DIHYDROQUERCITIN TO POSITIVELY INFLUENCE THE NATURAL PIGMENTATION PROCESS HENKEL AG & CO., KGAA (DE) 2012-05-10 US disclosed
WO-2011009759-A2 USE OF DIHYDROQUERCETIN AND AT LEAST ONE AMINO ACID TO POSITIVELY INFLUENCE THE NATURAL PIGMENTATION PROCESS HENKEL AG & CO. KGAA (DE) 2011-01-27 WO disclosed
WO-2011009761-A2 USE OF CARNITINE AND DIHYDROQUERCITIN TO POSITIVELY INFLUENCE THE NATURAL PIGMENTATION PROCESS HENKEL AG & CO. KGAA (DE) 2011-01-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150191430-A1 CONJUGATES OF HUPERZINE AND ANALOGS THEREOF HTT, HNMT, GAP43 MAPT 5/4885CYP3A4 2126/4885ALOX15 686/4885
US-20120115944-A1 USE OF CARNITINE AND DIHYDROQUERCITIN TO POSITIVELY INFLUENCE THE NATURAL PIGMENTATION PROCESS SLC25A20, CPT2, CRAT MAPT 2697/4885CYP3A4 3997/4885ALOX15 3758/4885
US-20120114583-A1 USE OF DIHYDROQUERCETIN AND AT LEAST ONE AMINO ACID TO POSITIVELY INFLUENCE THE NATURAL PIGMENTATION PROCESS TYR, TEAD2, TEAD3 MAPT 289/4885CYP3A4 4206/4885ALOX15 4630/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.