SCHEMBL10679583

SCHEMBL10679583

Oc1cc(-c2ccccc2)c2ccccc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 1.00
MEN1 O00255 2/20 1.00
KMT2A Q03164 2/20 1.00
ALDH1A1 P00352 1/20 1.00
MAPT P10636 1/20 1.00
HPGD P15428 1/20 1.00
MPI P34949 1/20 1.00
NQO2 P16083 1/20 0.57
BACE1 P56817 2/20 0.48
ALOX5 P09917 1/20 0.47
HSD17B1 P14061 1/20 0.46
HSD17B2 P37059 1/20 0.46
CDC25B P30305 1/20 0.46
CYP11B1 P15538 1/20 0.46
ESR1 P03372 2/20 0.45
ESR2 Q92731 2/20 0.45
GPR84 Q9NQS5 2/20 0.45
CDK4 P11802 1/20 0.44
CCND1 P24385 1/20 0.44
TRPM4 Q8TD43 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26367831 0.96 KDM4E (0.92) KDM4EMEN1KMT2AALDH1A1MAPT
SCHEMBL3031919 0.88 ALDH1A1 (0.79) KDM4EMEN1KMT2AALDH1A1MAPT
SCHEMBL31001020 0.87 ALDH1A1 (0.76) KDM4EMEN1KMT2AALDH1A1MAPT
SCHEMBL9052405 0.87 ALDH1A1 (0.76) KDM4EMEN1KMT2AALDH1A1MAPT
SCHEMBL7269797 0.85 ALDH1A1 (0.73) KDM4EMEN1KMT2AALDH1A1MAPT
SCHEMBL19765467 0.85 MEN1 (0.73) KDM4EMEN1KMT2AALDH1A1MAPT
SCHEMBL23569464 0.83 MEN1 (0.71) KDM4EMEN1KMT2AALDH1A1MAPT
SCHEMBL26367873 0.82 KDM4E (0.70) KDM4EMEN1KMT2AALDH1A1MAPT
SCHEMBL20362906 0.82 KDM4E (0.69) KDM4EMEN1KMT2AALDH1A1MAPT
SCHEMBL1791852 0.81 KDM4E (0.67) KDM4EMEN1KMT2AALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114874153-B Synthetic method of naphtho [2,1-d ] oxazole compound 湖南第一师范学院 2023-11-17 CN claimed
CN-114874153-A Synthetic method of naphtho [2,1-d ] oxazole compound 湖南第一师范学院 2022-08-09 CN claimed
WO-2025105827-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME 엘티소재주식회사 2025-05-22 WO disclosed
CN-117209343-A Continuous synthesis method of 2-naphthol compound 菏泽学院 2023-12-12 CN disclosed
US-20230391740-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LT MATERIALS CO., LTD. (KR) 2023-12-07 US disclosed
CN-114874153-B Synthetic method of naphtho [2,1-d ] oxazole compound 湖南第一师范学院 2023-11-17 CN disclosed
EP-4249477-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LT Materials Co., Ltd. (KR) 2023-09-27 EP disclosed
EP-4249477-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LT Materials Co., Ltd. (KR) 2023-09-27 EP disclosed
CN-116529245-A Compound and organic light-emitting element comprising same LT素材株式会社 2023-08-01 CN disclosed
CN-114874153-A Synthetic method of naphtho [2,1-d ] oxazole compound 湖南第一师范学院 2022-08-09 CN disclosed
WO-2022108068-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 엘티소재주식회사 2022-05-27 WO disclosed
US-10811612-B2 Organic electroluminescence device and electronic apparatus provided with the same IDEMITSU KOSAN CO., LTD. (JP) 2020-10-20 US disclosed
US-20200111965-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS PROVIDED WITH THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2020-04-09 US disclosed
US-20200111962-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS PROVIDED WITH THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2020-04-09 US disclosed
WO-2015157765-A1 SILANE COMPOUNDS AND METHODS OF USING THEREOF OHIO STATE INNOVATION FOUNDATION (US) 2015-10-15 WO disclosed
US-4788204-A TRANQUILIZERS; ANTICONVULSANTS; ANGINA AND IMMUNODIFICIENCY TREATMENTS RHONE-POULENC SANTE (FR) 1988-11-29 US disclosed
US-4788199-A ANXIOLYTICS, ANTICONVULSANTS, ANTIANGINA AGENTS RHONE-POULENC SANTE (FR) 1988-11-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200111965-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS PROVIDED WITH THE SAME RER1, RPS19, ESR1 KDM4E 1859/4885MEN1 1362/4885KMT2A 1933/4885
US-10811612-B2 Organic electroluminescence device and electronic apparatus provided with the same RER1, RPS19, ESR1 KDM4E 1859/4885MEN1 1362/4885KMT2A 1933/4885
US-20230391740-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME CRY1, CYP1B1, CYP1A1 KDM4E 2304/4885MEN1 243/4885KMT2A 1403/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.