Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.40 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.40 |
| ▸ | WNT3A | P56704 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.38 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10679859 | 0.80 | CTNNB1 (0.43) | KMT2AALDH1A1RAB9ACES2CES1 | |
| SCHEMBL10676766 | 0.79 | CDC7 (0.42) | KMT2AALDH1A1RAB9ACES2CES1 | |
| SCHEMBL10675049 | 0.79 | KMT2A (0.43) | KMT2AALDH1A1RAB9ACES2CES1 | |
| SCHEMBL10681828 | 0.78 | CDC7 (0.47) | KMT2AALDH1A1RAB9ACES2CES1 | |
| SCHEMBL7384310 | 0.76 | PDE3B (0.52) | KMT2AALDH1A1RAB9ALMNAKDM4E | |
| SCHEMBL7440629 | 0.76 | PDE3B (0.59) | KMT2AALDH1A1CES2CES1 | |
| SCHEMBL10680196 | 0.75 | PDE3B (0.58) | KMT2ALMNANAPRTKDM4ECDC7 | |
| SCHEMBL10680545 | 0.75 | ALDH1A1 (0.50) | ALDH1A1LMNAL3MBTL1KDM4ENPC1 | |
| SCHEMBL18557316 | 0.74 | KMT2A (0.53) | KMT2AALDH1A1RAB9ACES2CES1 | |
| SCHEMBL10809119 | 0.72 | HSD17B10 (0.39) | KMT2ANPC1CDC7GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4769380-A | Cardiotonic 5-benzoyl-1,2-dihydro-2-oxo-3-pyridinecarboxylates | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-09-06 | — | — | US | disclosed |