Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.39 |
| ▸ | WNT3A | P56704 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10681828 | 0.86 | CDC7 (0.47) | CDC7RAB9AKMT2ACTNNB1WNT3A | |
| SCHEMBL10679859 | 0.86 | CTNNB1 (0.43) | RAB9AKMT2ACTNNB1WNT3AKDM4E | |
| SCHEMBL10675049 | 0.85 | KMT2A (0.43) | CDC7RAB9AKMT2ACTNNB1WNT3A | |
| SCHEMBL7384310 | 0.82 | PDE3B (0.52) | RAB9AKMT2AKDM4EOPRK1GAA | |
| SCHEMBL10680545 | 0.81 | ALDH1A1 (0.50) | KDM4EGAAALDH1A1HPGDTSHR | |
| SCHEMBL10680104 | 0.79 | KMT2A (0.44) | CDC7RAB9AKMT2ACTNNB1WNT3A | |
| SCHEMBL10683120 | 0.78 | PDE3B (0.53) | CDC7KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL10675823 | 0.75 | CDC7 (0.38) | CDC7RAB9AKMT2AGAAALDH1A1 | |
| SCHEMBL7440629 | 0.75 | PDE3B (0.59) | KMT2AALDH1A1CES2CES1 | |
| SCHEMBL10678506 | 0.74 | CYP1A2 (0.39) | CDC7RAB9AKDM4ETSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4769380-A | Cardiotonic 5-benzoyl-1,2-dihydro-2-oxo-3-pyridinecarboxylates | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-09-06 | — | — | US | disclosed |